Passa al contenuto
Merck
Tutte le immagini(2)

Key Documents

View All Documentation

C8912

Sigma-Aldrich

Cocaine free base

Sinonimo/i:

Ecgonine methyl ester benzoate

Autenticatiper visualizzare i prezzi riservati alla tua organizzazione & contrattuali
Tutte le immagini(2)

About This Item

Formula empirica (notazione di Hill):
C17H21NO4
Numero CAS:
50-36-2
Peso molecolare:
303.35
Numero CE:
200-032-7
Numero MDL:
MFCD00056906
Codice UNSPSC:
12352200
ID PubChem:
24893116
NACRES:
NA.77

Forma fisica

powder

Controllo stupefacenti

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IB (Portugal)

applicazioni

forensics and toxicology

Stringa SMILE

[H][C@]12CC[C@]([H])([C@H]([C@H](C1)OC(=O)c3ccccc3)C(=O)OC)N2C

InChI

1S/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m0/s1
ZPUCINDJVBIVPJ-LJISPDSOSA-N

Informazioni sul gene

human ... DRD3(1814) , KCNH1(3756) , KCNH2(3757) , SCN10A(6336) , SCN11A(11280) , SCN5A(6331) , SLC6A2(6530) , SLC6A3(6531) , SLC6A4(6532)
mouse ... Slc6a2(20538)
rat ... Chrm1(25229) , Slc6a3(24898) , Slc6a4(25553)

Azioni biochim/fisiol

Inhibits the dopamine, norepinephrine, and serotonin transporters with Kis of about 300 nM, 900 nM, and 400 nM, respectively. Unlike amphetamines, it has no effect on catecholamine release.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H300 + H330,H336,H361d

Classi di pericolo

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Repr. 2 - STOT SE 3

Organi bersaglio

Central nervous system

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

Possiedi già questo prodotto?

I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

Visita l’Archivio dei documenti

Amanda Bruening et al.
Substance use & misuse, 54(11), 1825-1833 (2019-05-21)
Background: Research has noted that rates of recreational use of erectile dysfunction medication (EDM) are particularly high among men who have sex with other men. Though previous research has investigated recreational EDM use in relation to substance use, its association
Dieter Müller et al.
Clinical toxicology (Philadelphia, Pa.), 57(9), 806-812 (2019-02-19)
Introduction: Fentanyl derivatives like cyclopropylfentanyl have recently appeared on the recreational drug market. Cyclopropylfentanyl is probably a highly potent opioid, but human toxicological data are not available so far. Similar to other fentanyl derivatives the most serious acute health risk
Jesús Gómez-Bujedo et al.
The American journal of drug and alcohol abuse, 45(4), 365-376 (2019-01-15)
Background: Interpretation bias tasks such as word association tests have shown a moderate relation with substance use, but most studies have been conducted in nonclinical samples and these tasks are difficult to rate. Objectives: To provide: (1) reliability evidence of
Jennifer I Lissemore et al.
Translational psychiatry, 8(1), 82-82 (2018-04-19)
Cognitive behavioral therapy (CBT) and selective serotonin reuptake inhibitors (SSRIs) are both effective treatments for some patients with obsessive-compulsive disorder (OCD), yet little is known about the neurochemical changes related to these treatment modalities. Here, we used positron emission tomography
Tine van de Donk et al.
Pain, 160(4), 860-869 (2018-12-27)
In this experimental randomized placebo-controlled 4-way crossover trial, we explored the analgesic effects of inhaled pharmaceutical-grade cannabis in 20 chronic pain patients with fibromyalgia. We tested 4 different cannabis varieties with exact knowledge on their [INCREMENT]-tetrahydrocannabinol (THC) and cannabidiol (CBD)
Visualizza tutti i documenti correlati

Il team dei nostri ricercatori vanta grande esperienza in tutte le aree della ricerca quali Life Science, scienza dei materiali, sintesi chimica, cromatografia, discipline analitiche, ecc..

Contatta l'Assistenza Tecnica.