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Documenti fondamentali

C4582

Sigma-Aldrich

β-Carotene

synthetic, ≥95% (HPLC), crystalline

Sinonimo/i:

β,β-Carotene, Provitamin A

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About This Item

Formula empirica (notazione di Hill):
C40H56
Numero CAS:
Peso molecolare:
536.87
Beilstein:
1917416
Numero CE:
Numero MDL:
Codice UNSPSC:
12352212
ID PubChem:
NACRES:
NA.77

Origine biologica

synthetic

Livello qualitativo

Saggio

≥95% (HPLC)

Stato

crystalline

Impurezze

α-carotene, essentially free

Colore

dark red-purple to red-brown

Punto di fusione

178-179 °C

Solubilità

hexane: soluble 100 μg/mL
DMSO: 30 μg/mL
H2O: insoluble

ε (coefficiente d’estinzione)

2160-2280 at 478-479 nm in hexane at 1% (vs. 2280, lit.)
2450-2590 at 450-452 nm in hexane at 1% (vs. 2590, lit.)

Temperatura di conservazione

−20°C

Stringa SMILE

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C2=C(C)CCCC2(C)C)C(C)(C)CCC1

InChI

1S/C40H56/c1-31(19-13-21-33(3)25-27-37-35(5)23-15-29-39(37,7)8)17-11-12-18-32(2)20-14-22-34(4)26-28-38-36(6)24-16-30-40(38,9)10/h11-14,17-22,25-28H,15-16,23-24,29-30H2,1-10H3/b12-11+,19-13+,20-14+,27-25+,28-26+,31-17+,32-18+,33-21+,34-22+
OENHQHLEOONYIE-JLTXGRSLSA-N

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Applicazioni

β-Carotene has been used:
  • as standard for quantification of b-carotene using HPLC analysis
  • as a standard for the identification and quantification of authentic standards for carotenoid groups
  • for standard curve preparation in the measurement of β-carotene production
  • for standard curve preparation in nutritive assays

Azioni biochim/fisiol

β-Carotene (pro-vitamin A) is a member of carotenoids. This antioxidant plays a vital role in human physiology. β-Carotene is an abundant carotenoid. It is considered as a precursor of vitamin A, which is a lipid soluble antioxidant with vitamin E properties.
The most important of the provitamins A, β-carotene can be classified as an antioxidant due to its inhibition of radical initiated peroxidation in vitro. However, in vivo it appears to act either as an antioxidant or a prooxidant depending on cellular environment. It reduces the incidence of many cancers, but enhances lung cancer incidence in smokers.
The most important of the provitamins A.

Avvertenza

Purchase minimum quantity required. Discard one month after opening.

Applicazioni

N° Catalogo
Descrizione
Determinazione del prezzo

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

217.9 °F - closed cup

Punto d’infiammabilità (°C)

103.3 °C - closed cup

Dispositivi di protezione individuale

Eyeshields, Gloves


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Articoli

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Protocolli

HPLC Analysis of Carotene Compounds on Ascentis® RP-Amide

Chromatograms

application for HPLC

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