C4555
Methyl-β-cyclodextrin
powder, BioReagent, suitable for cell culture
About This Item
Prodotti consigliati
Origine biologica
synthetic (organic)
Livello qualitativo
Sterilità
non-sterile
Nome Commerciale
BioReagent
Stato
powder
PM
~1320 g/mol
Grado di funzionalizzazione
1.5-2.1 methyl per mol glucose
tecniche
cell culture | mammalian: suitable
Punto di fusione
180-182 °C (lit.)
Solubilità
H2O: 50 mg/mL
Temperatura di conservazione
room temp
Stringa SMILE
O1C2OC(C(OC3OC(C(OC4OC(C(OC5OC(C(OC6OC(C(OC7OC(C(OC8OC(C1C(C8OC)O)COC)C(C7OC)O)COC)C(C6OC)O)COC)C(C5OC)O)COC)C(C4OC)O)COC)C(C3OC)O)COC)C(C2OC)O)COC
InChI
1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3
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Categorie correlate
Descrizione generale
The solubility of natural cyclodextrins is very poor. In the late 1960′s, it was discovered that chemical substitutions at the 2, 3, and 6 hydroxyl sites would greatly increase solubility. Most chemically modified cyclodextrins are able to achieve a 50% (w/v) concentration in water.
Applicazioni
- to study the effect of cholesterol depletion, from sperm membrane on sperm′s ability to undergo acrosome reaction.
- to determine the effect of caveolin overexpression and its loss on pro-survival and pro-growth signaling
- in conventional in vitro fertilization
Azioni biochim/fisiol
Ricostituzione
Codice della classe di stoccaggio
11 - Combustible Solids
Classe di pericolosità dell'acqua (WGK)
WGK 3
Punto d’infiammabilità (°F)
368.6 °F
Punto d’infiammabilità (°C)
187 °C
Dispositivi di protezione individuale
Eyeshields, Gloves, type N95 (US)
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Articoli
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How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.
Many metabolically important compounds, such as lipid-soluble vitamins and hormones, have very low solubilities in aqueous solutions. Various techniques have been used to solubilize these compounds in tissue culture, cell culture, or other water-based applications.
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