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Key Documents

C1138

Sigma-Aldrich

ι-Carrageenan

commercial grade, Predominantly iota carrageenan

Sinonimo/i:

Vegetable gelatin

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About This Item

Numero CAS:
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
NACRES:
NA.25

Origine biologica

algae (Eucheuma spinosum)

Grado

commercial grade

Forma fisica

powder

Colore

beige

Intervallo di pH utile

8.0 - 10.5

Solubilità

water: soluble ~5 g/L

Temperatura di conservazione

room temp

InChI

1S/C24H38O31S4/c25-1-5-12(52-56(31,32)33)9(27)10(28)22(46-5)49-14-8-4-44-18(14)20(55-59(40,41)42)24(48-8)51-16-11(29)23(47-6(2-26)15(16)53-57(34,35)36)50-13-7-3-43-17(13)19(21(30)45-7)54-58(37,38)39/h5-30H,1-4H2,(H,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)/p-4/t5-,6-,7-,8-,9-,10-,11-,12+,13+,14+,15+,16-,17+,18+,19-,20-,21+,22+,23+,24-/m1/s1
QIDSWKFAPCTSKL-RRQHLKGPSA-J

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Descrizione generale

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.

Applicazioni

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-,and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities. ι-Carrageenan may be used to help define the role of carrageenan sulfation levels in physicochemical, biochemical, biological and pharmacological responses.

Nota sulla preparazione

Blended from various seaweeds to produce flexible gels.

Altre note

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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Jalles A Batista et al.
Carbohydrate polymers, 99, 59-67 (2013-11-28)
The sulfated polysaccharide (PLS) fraction of Agardhiella ramosissima was characterized by microanalysis, infrared spectroscopy, NMR and gas-liquid-chromatography-mass-spectrometry. The main constituent of PLS was the ι carrageenan. The monosaccharide composition of the PLS showed galactose, 3,6-anhydrogalactose and 6-O-methylgalactose. The PLS (30
Ritsu Nishimura et al.
Journal of medical and dental sciences, 60(1), 1-8 (2013-08-07)
Various gelatinizers, which facilitate oral ingestion, are employed in patients with dysphagia. The purpose of this study was to histologically clarify the influence of various gelatinizers on the lung, using rats. We administered 0.2 ml/kg of 0.1% xanthangam, a 0.25%
Kihyuck Kwak et al.
PloS one, 9(5), e97232-e97232 (2014-05-13)
The licensed human papillomavirus (HPV) vaccines elicit type-restricted immunity but do not target cutaneous HPV types of the beta genus that are associated with non-melanoma skin cancer in immune-compromised patients, and it is unclear if these diverse types share a
Andrew G Hettle et al.
Structure (London, England : 1993), 26(5), 747-758 (2018-04-24)
Sulfatases play a biologically important role by cleaving sulfate groups from molecules. They can be identified on the basis of signature sequences within their primary structures, and the largest family, S1, has predictable features that contribute specifically to the recognition
Andreas Sichert et al.
Nature microbiology, 5(8), 1026-1039 (2020-05-27)
Brown algae are important players in the global carbon cycle by fixing carbon dioxide into 1 Gt of biomass annually, yet the fate of fucoidan-their major cell wall polysaccharide-remains poorly understood. Microbial degradation of fucoidans is slower than that of other

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