B6936

3-Benzidino-6-(4-chlorophenyl)pyridazine

≥98% (HPLC), solid

• Sinonimo/i: BCP
• Formula empirica (notazione di Hill): C₂₂H₁₇N₄Cl
• Numero CAS: 901773-91-9
• Peso molecolare: 372.85
• Numero MDL: MFCD11046030
• Codice UNSPSC: 12352202
• ID PubChem: 329773289
• NACRES: NA.77

Proprietà

• Saggio: ≥98% (HPLC)
• Forma fisica: solid
• Colore: light yellow
• Solubilità: DMSO: >14 mg/mL
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2
• InChI: 1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27); ABGCSSPCKSVMHI-UHFFFAOYSA-N

Descrizione

Azioni biochim/fisiol

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

Caratteristiche e vantaggi

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301
• Consigli di prudenza: P264 - P270 - P301 + P310 - P405 - P501
• Classi di pericolo: Acute Tox. 3 Oral
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: dust mask type N95 (US), Eyeshields, Faceshields, Gloves