B4261

Biocytin

≥98% (TLC), suitable for drug transporter assays

• Sinonimo/i: Bct, N_ε-(+)-Biotinyl-L-lysine
• Formula empirica (notazione di Hill): C₁₆H₂₈N₄O₄S
• Numero CAS: 576-19-2
• Peso molecolare: 372.48
• Beilstein: 97197
• Numero MDL: MFCD00077319
• Codice UNSPSC: 12352209
• ID PubChem: 24891762
• NACRES: NA.26

Proprietà

• product name: Biocytin, ≥98% (TLC)
• Livello qualitativo: 200
• Saggio: ≥98% (TLC)
• Forma fisica: powder
• Attività ottica: [α]20/D +53°, c = 1.05% in 0.1 M NaOH(lit.)
• tecniche: drug transporter assay: suitable
• Colore: white to off-white
• Punto di fusione: ~245 °C (dec.) (lit.)
• Temperatura di conservazione: −20°C
• Stringa SMILE: [H][C@]12CS[C@@H](CCCCC(=O)NCCCC[C@H](N)C(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C16H28N4O4S/c17-10(15(22)23)5-3-4-8-18-13(21)7-2-1-6-12-14-11(9-25-12)19-16(24)20-14/h10-12,14H,1-9,17H2,(H,18,21)(H,22,23)(H2,19,20,24)/t10-,11-,12-,14-/m0/s1; BAQMYDQNMFBZNA-MNXVOIDGSA-N

Descrizione

Applicazioni

Biocytin is used as a substrate to study the specificity and kinetics of biotinidase(s), to measure biotinidase deficiency and as a model compound to study various uptake mechanisms of cells and tissues. Biocytin has been used to label neurons, medium spiny neurons and optic nerves.

Azioni biochim/fisiol

Biocytin is an adduct of lysine and biotin. It is hydrolyzed by biotinidase, which acts on peptide-incorporated biotin or free biotin. Biocytin acts as a coenzyme.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Gloves, type N95 (US)