A6419

Adenosina 5′-trifosfato

microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)

• Sinonimo/i: ATP
• Formula empirica (notazione di Hill): C₁₀H₁₄N₅Na₂O₁₃P₃ · xH₂O
• Numero CAS: 34369-07-8
• Peso molecolare: 551.14 (anhydrous basis)
• Numero MDL: MFCD00150755
• Codice UNSPSC: 12352207
• eCl@ss: 32160414
• ID PubChem: 24891086
• NACRES: NA.75

Proprietà

• Origine biologica: microbial
• Livello qualitativo: 200
• Nome Commerciale: BioReagent
• Saggio: ≥99% (HPLC)
• Forma fisica: powder
• tecniche: cell culture | mammalian: suitable
• Solubilità: H₂O: 50 mg/mL
• Temperatura di conservazione: −20°C
• Stringa SMILE: O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1; NTBQNWBHIXNPRU-MSQVLRTGSA-L

Descrizione

Descrizione generale

Adenosine 5′-triphosphate (ATP) is essential for biological processes including neurotransmission, signal transduction, muscle contraction and cardiac function. ATP is the major energy potential for living systems. They are released from cells under stress and play a key role in immune response. ATP release from injured neurons and consequent breakdown leads to generation of adenosine. ATP may serve as a therapeutic option in anaesthesia and intensive care medicine for the management of pain. Elevated ATP levels are indicative of cell damage and inflammation.

Applicazioni

Adenosine 5′-triphosphate disodium salt hydrate has been used:

• as a component of transfection mix for the transformation of CRISPR/Cas9 plasmid in parasites
• in inflammasome activation assays in bone marrow derived macrophages
• for the stimulation of macrophages
• in nucleotide synthesis

Azioni biochim/fisiol

Agonista purinergico P₂; aumenta l′attività dei canali K⁺ attivati da Ca²⁺; substrato per i sistemi enzimatici ATP-dipendenti

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable
• Dispositivi di protezione individuale: Eyeshields, Faceshields, Gloves, type N95 (US)