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A4937

Sigma-Aldrich

Anti-Mouse IgA (α-chain specific)−Alkaline Phosphatase antibody produced in goat

affinity isolated antibody, buffered aqueous glycerol solution

Sinonimo/i:

Goat Anti-Mouse IgA (α-chain specific)−AP

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About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

Origine biologica

goat

Livello qualitativo

Coniugato

alkaline phosphatase conjugate

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Stato

buffered aqueous glycerol solution

tecniche

direct ELISA: 1:30,000
western blot: 1:30,000

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Categorie correlate

Descrizione generale

Immunoglobulin A (IgA) is the major mammalian antibody isotype that is synthesized in the gut associated lymphoid tissues. This immunoglobulin isotype modulates intestinal microorganisms and has been implicated in the pathogenesis of IgA nephropathy. Anti-Mouse IgA (α-chain specific)-Alkaline Phosphatase antibody is specific for mouse IgA when tested against purified mouse IgA, IgG, and IgM myeloma proteins.

Immunogeno

Purified mouse IgA

Applicazioni

E. coli lysates and purified pili were analyzed by western blot using alkaline phosphatase conjugated goat anti-mouse IgA antibody as a secondary.
Anti-Mouse IgA (α-chain specific)-Alkaline Phosphatase antibody is suitable for use in ELISA. The product can also be used for western blot (1:30,000).

Stato fisico

Solution in 0.05 M Tris, pH 8.0, containing 1 mM MgCl2, 10 mM glycine, 1% bovine serum albumin, 50% glycerol and 15 mM sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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Young Youl Hyun et al.
Cell transplantation, 21(11), 2425-2439 (2012-04-25)
T-cell dysregulation plays an important role in the pathogenesis of immunoglobulin A nephropathy (IgAN). Adipose-derived stem cells (ASCs) have been reported to be able to prevent tissue damage through immune-modulating effects. To evaluate the effects of ASCs in high IgA
P J Valentine et al.
Infection and immunity, 66(7), 3378-3383 (1998-06-25)
A panel of Salmonella typhimurium 14028s mutants, which were previously shown to be highly attenuated in the BALB/c mouse model of infection, were analyzed for their potential as live Salmonella oral-vaccine candidates. A prototypical aroA mutant was chosen as a
Anna U Bielinska et al.
Infection and immunity, 75(8), 4020-4029 (2007-05-16)
The currently available commercial human anthrax vaccine requires multiple injections for efficacy and has side effects due to its alum adjuvant. These factors limit its utility when immunizing exposed populations in emergent situations. We evaluated a novel mucosal adjuvant that
Finn Terje Hegge et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(29), 10798-10803 (2004-07-14)
Several major bacterial pathogens and related commensal species colonizing the human mucosa express phosphocholine (PC) at their cell surfaces. PC appears to impact host-microbe biology by serving as a ligand for both C-reactive protein and the receptor for platelet-activating factor.
Duncan B Sutherland et al.
Current opinion in immunology, 24(3), 261-268 (2012-04-17)
Immunoglobulin A (IgA) is the most abundantly produced antibody isotype in mammals. The primary function of IgA is to maintain homeostasis at mucosal surfaces. IgA is generated in specialized gut associated lymphoid tissues (GALT) by T cell-dependent and T cell-independent

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