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A2504

Sigma-Aldrich

6-Aminocaproic acid

≥99% (titration), powder

Sinonimo/i:

ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA

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About This Item

Formula condensata:
H2N(CH2)5CO2H
Numero CAS:
60-32-2
Peso molecolare:
131.17
Beilstein:
906872
Numero CE:
200-469-3
Numero MDL:
MFCD00008238
Codice UNSPSC:
12352202
ID PubChem:
24890662
NACRES:
NA.77

Origine biologica

synthetic

Livello qualitativo

300

Saggio

≥99% (titration)

Forma fisica

powder

tecniche

cell culture | mammalian: suitable

Colore

white

Punto di fusione

207-209 °C (dec.) (lit.)

Solubilità

H2O: 50 mg/mL

Stringa SMILE

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)
SLXKOJJOQWFEFD-UHFFFAOYSA-N

Informazioni sul gene

human ... PLAT(5327) , PLG(5340)
rat ... Ppm1a(24666)

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Categorie correlate

Applicazioni

EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.

Azioni biochim/fisiol

EACA is reported to inhibit chymotrypsin, Factor VIIa, lysine carbo­xy­peptidase, plasmin, and plasminogen activator.
Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

404.6 - 408.2 °F

Punto d’infiammabilità (°C)

207 - 209 °C

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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