A2419
ω-Aminohexyl–Sepharose™ 4B
aqueous ethanol suspension
Sinonimo/i:
ψ-Aminohexyl Resin, Aminohexyl Sepharose
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About This Item
Prodotti consigliati
Stato
aqueous ethanol suspension
Livello qualitativo
tecniche
affinity chromatography: suitable
Attivazione matrice
epoxy
Gruppi immobilizzati alla matrice
amino
Braccio spaziatore
11 atoms
Temperatura di conservazione
2-8°C
Applicazioni
ω-Aminohexyl– Sepharose™ 4B is used mainly in affinity chromatography. It has been used in mitochondrial research to purify thioredoxin reductase (TrxR2), which is important in cell signaling and may also be an anticancer drug target.
Stato fisico
Suspension in 20% ethanol.
Note legali
Sepharose is a trademark of Cytiva
Avvertenze
Warning
Indicazioni di pericolo
Consigli di prudenza
Classi di pericolo
Flam. Liq. 3
Codice della classe di stoccaggio
3 - Flammable liquids
Classe di pericolosità dell'acqua (WGK)
WGK 1
Punto d’infiammabilità (°F)
95.0 °F
Punto d’infiammabilità (°C)
35 °C
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Methods in enzymology, 474, 109-122 (2010-07-09)
Mitochondrial thioredoxin reductase (TrxR2) maintains thioredoxin (Trx2) in a reduced state and plays a critical role in mitochondrial and cellular functions. TrxR2 has been identified in many different tissues and can be purified to homogeneity from whole organs and isolated
The Biochemical journal, 207(3), 459-470 (1982-12-01)
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Seminars in cancer biology, 16(6), 452-465 (2006-10-24)
Thioredoxin reductase (TrxR)-as part of a major thiol regulating system-allows redox metabolism to adjust to cellular requirements. Therefore, changes at the redox level reflect as a pars pro toto changes concerning the entire cell. Three different TrxR isoenzymes, TrxR1 as
The Journal of biological chemistry, 267(5), 3498-3505 (1992-02-15)
The chick kidney mitochondrial cytochrome P-450 1,25-dihydroxyvitamin D3 24-hydroxylase was partially purified by sequential polyethylene glycol precipitation, aminohexyl-Sepharose 4B, and hydroxylapatite chromatography. The specific activity of the final preparation, when reconstituted with NADPH, adrenodoxin, and adrenodoxin reductase, was 245 pmol/min/mg
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