A2351

Anti-ADAM-8, Propeptide Domain antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Sinonimo/i: Anti-A Disintegrin And Metalloproteinase-8, Anti-CD156, Anti-MS2
• Numero MDL: MFCD04040160
• Codice UNSPSC: 12352203
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 200
• Coniugato: unconjugated
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Forma fisica: buffered aqueous glycerol solution
• Reattività contro le specie: rat, human, pig
• Concentrazione: ~1 mg/mL
• tecniche: western blot: 1:1,000
• N° accesso UniProt: P78325
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: −20°C
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ADAM8(101) ; pig ... ADAM8(100156146) ; rat ... Tubgcp2(309098)

Descrizione

Descrizione generale

ADAM8, a transmembrane glycoprotein, also known as MS2 and CD156, is a member of the metalloproteinase family containing disintegrin-like domains (ADAMs). ADAM8 is up-regulated in the central nervous system following neurogeneration and activation of glia, astrocytes, and microglia, suggesting that it may have a role in neuron-glia interactions. ADAM8 stimulates osteoclasts, suggesting a role in cell adhesion and cell fusion.
Anti-ADAM-8, propeptide domain antibody localizes human, porcine, and rat ADAM8 and does not react with other ADAMs. In immunoblotting assays against the reduced protein, the antibody recognizes 52kDa and 70kDa bands in conditioned media or cell lysates. In culture media, the 52kDa form is predominant.

Immunogeno

synthetic peptide corresponding to the propeptide domain of human ADAM-8.

Applicazioni

Anti-ADAM-8, propeptide domain antibody can be used for western blotting assays at a dilution of 1:1,000.

Stato fisico

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids