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Documenti

64951

Sigma-Aldrich

7-Methoxycoumarin

suitable for fluorescence, ≥98.0% (TLC)

Sinonimo/i:

Herniarin, Methyl umbelliferyl ether

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About This Item

Formula empirica (notazione di Hill):
C10H8O3
Numero CAS:
531-59-9
Peso molecolare:
176.17
Beilstein:
141728
Numero CE:
208-513-3
Numero MDL:
MFCD00006876
Codice UNSPSC:
85151701
ID PubChem:
57651999
NACRES:
NA.32

Saggio

≥98.0% (TLC)

Forma fisica

solid

Punto di fusione

117-121 °C (lit.)

Solubilità

DMF: soluble
acetonitrile: soluble
alcohols: soluble
chloroform: soluble

Fluorescenza

λex 350 nm; λem 385 nm (Reaction product)
λex 350 nm; λem 385 nm in chloroform

Compatibilità

suitable for fluorescence

Stringa SMILE

COc1ccc2C=CC(=O)Oc2c1

InChI

1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3
LIIALPBMIOVAHH-UHFFFAOYSA-N

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Applicazioni

7-Methoxycoumarin (Herniarin) is used to study antioxidant and hepatoprotective properties and its activity as an allergen. 7-Methoxycoumarin may be used as a reference material in the purification, separation and analysis of coumarin compounds.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

Certificati d'analisi (COA)

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The available conventional remedies for the treatment of drug-induced liver diseases are highly inadequate and possess serious adverse effects; therefore, the development of new, effective drugs is considered necessary. This article explores the hepatoprotective and antioxidant potential of 7-methylcoumarin (MC)
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Although German chamomile (Chamomilla recutita) is considered a weak sensitizer, recent studies have shown several possible non-sesquiterpene lactone allergens in tea (infusions) from the plant. The aim of this study was to report the results of patch testing with herniarin
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Chamomile (Matricaria chamomilla) in the above-ground organs synthesizes and accumulates (Z)- and (E)-2-beta-D: -glucopyranosyloxy-4-methoxy cinnamic acids (GMCA), the precursors of phytoanticipin herniarin (7-methoxycoumarin). The diurnal rhythmicity of the sum of GMCA (maximum before daybreak) and herniarin (acrophase at 10 h
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