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49549

Sigma-Aldrich

4-Hydroxy-L-isoleucine

≥98.0% (TLC)

Sinonimo/i:

(2S,3R)-2-Amino-4-hydroxy-3-methylpentanoic acid

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About This Item

Formula empirica (notazione di Hill):
C6H13NO3
Numero CAS:
781658-23-9
Peso molecolare:
147.17
Numero MDL:
MFCD06799350
Codice UNSPSC:
12352204
eCl@ss:
32160406
ID PubChem:
329757475
NACRES:
NA.32

product name

4-Hydroxy-L-isoleucine, ≥98.0% (TLC)

Saggio

≥98.0% (TLC)

Attività ottica

[α]/D +34.0±2.0°, c = 1 in H2O

Colore

white to off-white

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(O)[C@H](C)[C@H](N)C(O)=O

InChI

1S/C6H13NO3/c1-3(4(2)8)5(7)6(9)10/h3-5,8H,7H2,1-2H3,(H,9,10)/t3-,4?,5-/m0/s1
OSCCDBFHNMXNME-DSDZBIDZSA-N

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Azioni biochim/fisiol

A peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity; effects on insulin secretion, plant-derived treatment for metabolic syndrome.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Consigli di prudenza

P261 - P305 + P351 + P338

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

296.6 °F

Punto d’infiammabilità (°C)

147 °C

Certificati d'analisi (COA)

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C Broca et al.
European journal of pharmacology, 390(3), 339-345 (2000-03-10)
4-Hydroxyisoleucine, a peculiar amino acid extracted from fenugreek seeds and never found in mammalian tissues, exhibits interesting insulinotropic activity. To investigate the structural requirements for this stimulating effect, the insulinotropic activity of the major isomer (2S,3R,4S) of 4-hydroxyisoleucine, in the
Dong Hoon Shin et al.
Annals of laboratory medicine, 34(4), 307-312 (2014-07-02)
Hemolysis, icterus, and lipemia (HIL) cause preanalytical interference and vary unpredictably with different analytical equipments and measurement methods. We developed an integrated reporting system for verifying HIL status in order to identify the extent of interference by HIL on clinical
Zhi Zhang et al.
PloS one, 8(4), e62909-e62909 (2013-05-03)
Natural populations of the fruit fly, Drosophila melanogaster, segregate genetic variation that leads to cardiac disease phenotypes. One nearly isogenic line from a North Carolina peach orchard, WE70, is shown to harbor two genetically distinct heart phenotypes: elevated incidence of
Jasmin Dischinger et al.
PloS one, 4(8), e6788-e6788 (2009-08-27)
Lantibiotics are small microbial peptide antibiotics that are characterized by the presence of the thioether amino acids lanthionine and methyllanthionine. Lantibiotics possess structural genes which encode inactive prepeptides. During maturation, the prepeptide undergoes posttranslational modifications including the introduction of rare
Anna Maria Herzner et al.
PloS one, 6(7), e22389-e22389 (2011-08-04)
Lantibiotics are small peptide antibiotics that contain the characteristic thioether amino acids lanthionine and methyllanthionine. As ribosomally synthesized peptides, lantibiotics possess biosynthetic gene clusters which contain the structural gene (lanA) as well as the other genes which are involved in
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