483R-1

p40 (ZR8) Rabbit Monoclonal Antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100; 500
• Coniugato: unconjugated
• Forma dell’anticorpo: culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: ZR8
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Forma fisica: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL concentrate (483R-14); vial of 0.1 mL concentrate, Research Use Only (483R-14-RUO); vial of 0.5 mL concentrate (483R-15); vial of 1.0 mL concentrate (483R-16); vial of 1.0 mL concentrate, Research Use Only (483R-16-RUO); vial of 1.0 mL pre-dilute, Research Use Only (483R-17-RUO); vial of 1.0 mL pre-dilute, ready to use (483R-17); vial of 25.0 mL pre-dilute, ready-to-use (483R-10); vial of 25.0 mL pre-dilute, ready-to-use, Research Use Only (483R-10-RUO); vial of 7.0 mL pre-dilute, ready to use (483R-18); vial of 7.0 mL pre-dilute, ready to use, Research Use Only (483R-18-RUO)
• Produttore/marchio commerciale: Cell Marque
• tecniche: immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable (1:100-1:200 (concentrated))
• Isotipo: IgG
• Controllo: lung (squamous cell carcinoma), prostate, urothelial carcinoma
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: nuclear

Descrizione

Descrizione generale

p40 is an isoform of p63, a transcription factor that regulates many cell activities, including cell proliferation, maintenance, and differentiation. It performs as a sensitive and specific tool for aiding in the identification of squamous cell carcinoma of the lung. In addition to its utility as a squamous differentiation marker, p40 has also been proven to be a valuable marker for highlighting myoepithelial and basal cell populations in prostate, breast, skin, and salivary gland.^1-5 Strong p40 expression is frequently observed in esophageal cancerous squamous lesions.⁶ Immunohistochemical detection of p40 can also be helpful in identifying urothelial carcinoma.⁷ In cases of prostate carcinoma, p40 is almost always found to be negative for basal cell staining.⁸

Qualità

• United States - IVD
• Canada - RUO
• European Union - IVD
• Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

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Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable