363R-3

PAX-8 (SP348) Rabbit Monoclonal Antibody

• Codice UNSPSC: 12352203

Proprietà

• Origine biologica: rabbit blood
• Livello qualitativo: 500
• Coniugato: unconjugated
• Forma dell’anticorpo: IgG fraction of tissue culture supernatant
• Tipo di anticorpo: primary antibodies
• Clone: SP348
• Descrizione: For In Vitro Diagnostic Use in Select Regions
• Stato: buffered aqueous solution
• Reattività contro le specie: human
• Confezionamento: vial of 0.1 mL (concentrate (363R-34-RUO) Research Use Only); vial of 0.1 mL ; (concentrate (363R-34)); vial of 0.5 mL (concentrate (363R-35)); vial of 1.0 mL (concentrate (363R-36)); vial of 1.0 mL (concentrate (363R-36-RUO) Research Use Only); vial of 1.0 mL (pre-dilute (363R-37-RUO) Research Use Only); vial of 1.0 mL (pre-dilute ready-to-use (363R-37)); vial of 25.0 mL (pre-dilute ready-to-use (363R-30)); vial of 25.0 mL (pre-dilute ready-to-use (363R-30-RUO)); vial of 7.0 mL (pre-dilute ready-to-use (363R-38)); vial of 7.0 mL (pre-dilute ready-to-use (363R-38-RUO) Research Use Only)
• Produttore/marchio commerciale: Cell Marque^™
• tecniche: immunocytochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:10-1:20 (concentrated))
• Isotipo: IgG
• Controllo: ovarian carcinoma, papillary carcinoma of thyroid, renal cell carcinoma, (Fallopian Tube)
• Condizioni di spedizione: wet ice
• Temperatura di conservazione: 2-8°C
• Visualizzazione: nuclear

Descrizione

Descrizione generale

PAX-8 is a transcription factor expressed during embryonic development of Müllerian organs, kidney, and thyroid, with continued expression in neoplastic transformation of some epithelial cell types of these mature tissues.1 It can be useful for marking several types of carcinoma including, but not limited to, ovarian serous carcinoma, clear cell renal cell carcinoma and papillary thyroid carcinoma. Certain anti-PAX-8 antibodies may react with lymphocytes and their neoplasms, which has been attributed to cross-reactivity with PAX-5 due to sequence homology between PAX-8 and PAX-5, but clone SP348 does not exhibit reactivity in these cell types.

Qualità

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Nota sulla preparazione

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Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2