30891

Biliverdin hydrochloride

≥97.0% (TLC)

• Sinonimo/i: Biliverdin
• Formula empirica (notazione di Hill): C₃₃H₃₄N₄O₆ · HCl
• Numero CAS: 856699-18-8
• Peso molecolare: 619.11
• Codice UNSPSC: 12352204
• ID PubChem: 329753599
• NACRES: NA.32

Proprietà

• Saggio: ≥97.0% (TLC)
• Forma fisica: powder or crystals
• applicazioni: metabolomics; vitamins, nutraceuticals, and natural products
• Temperatura di conservazione: −20°C
• Stringa SMILE: Cl.CC1=C(C=C)C(\NC1=O)=C\c2[nH]c(/C=C3\N=C(\C=C4/NC(=O)C(C=C)=C4C)C(C)=C3CCC(O)=O)c(CCC(O)=O)c2C
• InChI: 1S/C33H34N4O6.ClH/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26;/h7-8,13-15,35H,1-2,9-12H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41);1H/b26-13-,27-14-,28-15-;; KTRFJVRKVQROKS-UJCZHUFNSA-N

Descrizione

Descrizione generale

Biliverdin (BV) is considered as a near-infrared (NIR)-absorbing pigment, that is endogenic. It is a linear tetrapyrrolic intermediate of heme degradation (heme catabolism) to bilirubin. The bile of amphibia and birds contains only biliverdine, no bilirubin.

Applicazioni

Biliverdin hydrochloride has been used:

• as a treatment to J774A.1 cells to study its role in alternation of beta (β)-endorphins level
• as a commercial standard for the detection of biliverdin in mouse unstable and stable plaques tissues using liquid chromatography-tandem mass spectrometry (LC-MS-MS)
• to add to Fucci-containing cells to improve the mIFP signal
• to examine its impact on infrared fluorescent protein (iRFP) in some retinal preparations

Azioni biochim/fisiol

Biliverdin (BV) is an excellent anti-inflammatory agent that protects against lipopolysaccharides (LPS)-induced lung injury in mouse endothelial cells. It aids protection in polymicrobial sepsis. Biliverdin has cytoprotective effects on rat livers and protects from prolonged ischemia and reperfusion injury. It also shows antioxidant activities.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Informazioni sulla sicurezza

• Pittogrammi: GHS07
• Avvertenze: Warning
• Indicazioni di pericolo: H315,H319,H335
• Consigli di prudenza: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classi di pericolo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Organi bersaglio: Respiratory system
• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable