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Merck
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Key Documents

293M-9

Sigma-Aldrich

MUC6 (MRQ-20) Mouse Monoclonal Antibody

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About This Item

Codice UNSPSC:
12352203
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100
500

Coniugato

unconjugated

Forma dell’anticorpo

diluted ascites fluid

Tipo di anticorpo

primary antibodies

Clone

MRQ-20, monoclonal

Descrizione

For In Vitro Diagnostic Use in Select Regions (See Chart)

Forma fisica

buffered aqueous solution

Reattività contro le specie

human

Confezionamento

vial of 0.1 mL concentrate (293M-94)
vial of 0.5 mL concentrate (293M-95)
bottle of 1.0 mL predilute (293M-97)
vial of 1.0 mL concentrate (293M-96)
bottle of 7.0 mL predilute (293M-98)

Produttore/marchio commerciale

Cell Marque™

tecniche

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotipo

IgG1

Controllo

stomach

Condizioni di spedizione

wet ice

Temperatura di conservazione

2-8°C

Visualizzazione

cytoplasmic

Informazioni sul gene

human ... MUC6(4588)

Categorie correlate

Descrizione generale

MUC6 is a secretory mucin that is part of a family of at least 14 high molecular-weightglycoproteins made by many epithelial tissues. MUC6 is preferentially expressed in nonneoplastic gastric tissue, specifically in the pyloric glands. During neoplastic transformation,mucin expression may be altered within these tissues leading to particular patterns ofexpression.

Qualità


IVD
IVD
IVD
RUO

Linkage

MUC6 Positive Control Slides, Product No. 293S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Stato fisico

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Nota sulla preparazione

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Altre note

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Note legali

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Emad A Rakha et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 18(10), 1295-1304 (2005-06-25)
Mucins are a large family of glycoproteins expressed by many epithelial cells and their malignant counterparts. Much interest has been focused on expression of its members in breast cancer because of their potential role as prognostic indicators and their involvement
Seog-Yun Park et al.
Archives of pathology & laboratory medicine, 131(10), 1561-1567 (2007-10-10)
Although identification of the primary tumor in patients with metastatic adenocarcinoma has a profound clinical impact, diagnosing the organ of origin is frequently difficult. Because none of the individual immunohistochemical markers used for tissue identification are both site specific and
P Chaves et al.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 18(6), 383-387 (2005-12-13)
Intestinal metaplasia is a prerequisite criterion for the diagnosis of Barrett's metaplasia and the sole columnar esophageal lining associated with malignancy. It is recognized by the presence of goblet cells, but columnar non-goblet elements, producing gastric or intestinal proteins, are
Fionnuala P O'Connell et al.
Archives of pathology & laboratory medicine, 129(3), 338-347 (2005-03-02)
Breast carcinoma often metastasizes to the gastrointestinal tract, especially the stomach, where it is frequently difficult to distinguish from a primary gastric carcinoma. To evaluate the utility of immunohistochemical stains in differentiating primary gastric carcinomas from metastatic breast carcinomas. Mucosal
T Mizoshita et al.
Histology and histopathology, 22(3), 251-260 (2006-12-14)
We have previously demonstrated links between clinicopathological findings and phenotypes using several gastric and intestinal phenotypic markers in stomach and pancreatic cancers. However, the clinicopathological significance of the phenotype and Cdx2 expression has hitherto remained unclear in colorectal carcinogenesis. We
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