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Key Documents

T0050000

Terbutaline sulfate

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Terbutaline hemisulfate salt, 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol hemisulfate salt

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About This Item

Formula condensata:
C12H19NO3 · 1/2H2SO4
Numero CAS:
Peso molecolare:
274.32
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

terbutaline

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

OS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c2cc(O)cc(O)c2

InChI

1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
KFVSLSTULZVNPG-UHFFFAOYSA-N

Informazioni sul gene

human ... ADRB2(154)

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Terbutaline sulfate EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Pittogrammi

Health hazard

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Repr. 2 - STOT SE 1

Organi bersaglio

Cardio-vascular system

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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F Lam et al.
Obstetrical & gynecological survey, 53(11 Suppl), S85-S95 (1998-11-13)
beta-mimetics have been prescribed by physicians to arrest or prevent premature labor for more than 20 years. Although not approved by the Food and Drug Administration (FDA) for tocolytic use, terbutaline sulfate has been the most widely prescribed beta-mimetic in
C H Scoggin
Clinical therapeutics, 6(5), 603-612 (1984-01-01)
Terbutaline sulfate, a relatively selective beta2 agonist, is indicated for the treatment of bronchospasm associated with chronic obstructive pulmonary disease. Studies have shown that when administered via an aerosol, terbutaline has a rapid onset, a prolonged duration of action, and
Adel H Mansur et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(10), 1076-1082 (2014-07-16)
Long-term subcutaneous or intravenous infusion of terbutaline has been used to stabilize asthma in patients enduring frequent hospital admissions due to severe asthma despite maximum therapy. However, this treatment is not supported by significant body of evidence. To study long-term
John P Elliott et al.
The Journal of reproductive medicine, 58(3-4), 123-131 (2013-04-02)
Beta2-adrenergic agonist medications such as albuterol and terbutaline are often prescribed during pregnancy to treat conditions such as asthma, pulmonary disease, preterm labor, or acute non-reassuring fetal heart rate abnormalities during labor. Recently a review article questioned the safety of
Srinivas R B Behara et al.
Journal of pharmaceutical sciences, 103(2), 465-477 (2013-12-07)
High-efficiency dry powder inhalers (DPIs) were developed and tested for use with carrier-free formulations across a range of different inhalation flow rates. Performance of a previously reported DPI was compared with two new designs in terms of emitted dose (ED)

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