SMB01335

N¹-Acetyl-N²-formyl-5-methoxykynuramine

≥95% (HPLC)

• Sinonimo/i: AFMK, AFMKA, NSC-688263, NSC688263, N-[3-[2-(Formylamino)-5-methoxyphenyl]-3-oxopropyl]acetamide, NSC 688263
• Formula empirica (notazione di Hill): C₁₃H₁₆N₂O₄
• Numero CAS: 52450-38-1
• Peso molecolare: 264.28
• Numero MDL: MFCD02683241
• Codice UNSPSC: 12352116
• NACRES: NA.77

Proprietà

• Livello qualitativo: 200
• Saggio: ≥95% (HPLC)
• Forma fisica: solid
• Temperatura di conservazione: 2-8°C
• Stringa SMILE: COc1ccc(NC=O)c(c1)C(=O)CCNC(C)=O
• InChI: 1S/C13H16N2O4/c1-9(17)14-6-5-13(18)11-7-10(19-2)3-4-12(11)15-8-16/h3-4,7-8H,5-6H2,1-2H3,(H,14,17)(H,15,16); JYWNYMJKURVPFH-UHFFFAOYSA-N

Descrizione

Descrizione generale

Melatonin and its metabolites are being studied for their antioxidant properties and their protective effects against oxidative stress in both mammals and in plants. N¹-Acetyl-5-methoxykynuramine (AMK) and its direct precursor N¹-acetyl-N²-formyl-5-methoxykynuramine (AFMK) are two metabolites that contribute to the antioxidant properties of melatonin.

Applicazioni

Metabolomics research

Azioni biochim/fisiol

AFMK is a melatonin metabolite first detected in rat brain; demonstrates antioxidant and free radical scavenging activities in several experimental models; inhibits LPS-mediated production of TNFα and IL-8 in neutrophils; useful tool in the study of melatonin metabolism.

Informazioni sulla sicurezza

• Pittogrammi: GHS06
• Avvertenze: Danger
• Indicazioni di pericolo: H301
• Consigli di prudenza: P264 - P270 - P301 + P310 - P405 - P501
• Classi di pericolo: Acute Tox. 3 Oral
• Codice della classe di stoccaggio: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable