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S1148

Sigma-Aldrich

SBFI-AM

≥80% purity

Sinonimo/i:

Sodium indicator SBFI-AM, Sodium-binding benzofuran isophthalate-AM

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About This Item

Formula empirica (notazione di Hill):
C56H58N2O23
Numero CAS:
129423-53-6
Peso molecolare:
1127.06
Numero MDL:
MFCD00082576
Codice UNSPSC:
12171500
ID PubChem:
24899463
NACRES:
NA.47

product name

SBFI-AM,

Temperatura di conservazione

−20°C

Livello qualitativo

200

Stringa SMILE

COc1cc2cc(oc2cc1N3CCOCCOCCN(CCOCC3)c4cc5oc(cc5cc4OC)-c6ccc(cc6C(=O)OCOC(C)=O)C(=O)OCOC(C)=O)-c7ccc(cc7C(=O)OCOC(C)=O)C(=O)OCOC(C)=O

InChI

1S/C56H58N2O23/c1-33(59)72-29-76-53(63)37-7-9-41(43(21-37)55(65)78-31-74-35(3)61)49-23-39-25-51(67-5)45(27-47(39)80-49)57-11-15-69-16-12-58(14-18-71-20-19-70-17-13-57)46-28-48-40(26-52(46)68-6)24-50(81-48)42-10-8-38(54(64)77-30-73-34(2)60)22-44(42)56(66)79-32-75-36(4)62/h7-10,21-28H,11-20,29-32H2,1-6H3
MWUYLQGOGOLRQS-UHFFFAOYSA-N

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Applicazioni

Cell permeant sodium selective fluorescent indicator

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLBW8188
SLBW1395
SLBV2402
SLBR9957V
SLBQ4712V

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I documenti relativi ai prodotti acquistati recentemente sono disponibili nell’Archivio dei documenti.

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G Cristina Brailoiu et al.
Drug and alcohol dependence, 178, 7-14 (2017-06-18)
HIV-1 infection and drug abuse are frequently co-morbid and their association greatly increases the severity of HIV-1-induced neuropathology. While nucleus accumbens (NAcc) function is severely perturbed by drugs of abuse, little is known about how HIV-1 infection affects NAcc. We
Bruno A Cisterna et al.
Nature communications, 11(1), 1073-1073 (2020-02-28)
Denervation of skeletal muscles induces severe muscle atrophy, which is preceded by cellular alterations such as increased plasma membrane permeability, reduced resting membrane potential and accelerated protein catabolism. The factors that induce these changes remain unknown. Conversely, functional recovery following
A Minta et al.
The Journal of biological chemistry, 264(32), 19449-19457 (1989-11-15)
Fluorescent indicators sensitive to cytosolic concentrations of free Na+ have been synthesized and characterized. They consist of a crown ether, 1,7-diaza-4,10,13-trioxacyclopentadecane, linked via its nitrogens to fluorophores bearing additional liganding centers. In the currently preferred dye, SBFI (short for sodium-binding
X Chen et al.
Biochemistry, 33(46), 13769-13774 (1994-11-22)
Although the predominance of plasmalogens in electrically-active membranes (e.g., sarcolemma) is well-known, identification of the molecular mechanisms through which the vinyl ether linkage facilitates electrophysiologic function has remained elusive. Herein we demonstrate that the kinetics of both carrier-mediated (i.e., valinomycin)
Sung-Kyun Ko et al.
Nature chemistry, 6(10), 885-892 (2014-09-23)
Anion transporters based on small molecules have received attention as therapeutic agents because of their potential to disrupt cellular ion homeostasis. However, a direct correlation between a change in cellular chloride anion concentration and cytotoxicity has not been established for
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