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S0900000

Sodium taurocholate

BRP, European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

Taurocholic acid sodium salt

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About This Item

Formula empirica (notazione di Hill):
C26H44NNaO7S
Numero CAS:
145-42-6
Peso molecolare:
537.68
Beilstein:
3901620
Numero CE:
205-653-7
Numero MDL:
MFCD00013050
Codice UNSPSC:
41116107
ID PubChem:
329824184
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

sodium taurocholate

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

InChI

1S/C26H45NO7S.Na.H/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29;;/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34);;/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-;;/m1../s1
VXRNGJZKPMKERN-NEMAEHQESA-N

Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Anionic detergent used for protein solubilization.

Azioni biochim/fisiol

Non-sulfated bile salt, physiological transport substrate for the bile salt export pump/sister of Pgp (BSEP/spgp), Na(+)/taurocholate cotransporter (NTCP) and MRP3 into the hepatic carnalicular.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number

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Taurocholic Acid, Sodium Salt ULTROL® Grade, ≥98% (TLC), detergent to solubilize membrane-bound proteins in their native state

Millipore

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vibrant-m

Y0001631

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Cholic acid-2,2,3,4,4-d5 98 atom % D, 98% (CP)

Sigma-Aldrich

614106

Cholic acid-2,2,3,4,4-d5

Acido 4-nitrobenzoico United States Pharmacopeia (USP) Reference Standard

USP

1466572

Acido 4-nitrobenzoico

Bile salts suitable for microbiology

Millipore

48305

Bile salts

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Journal of nutritional science and vitaminology, 62(5), 335-340 (2016-12-09)
Several studies have suggested that resistant maltodextrin (RMD) suppresses intestinal lipid absorption in experimental animals and humans. However, possible mechanisms underlying this effect are not known. In this study, effects of RMD on processes of the absorption of various lipids
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Scientific reports, 10(1), 9052-9052 (2020-06-05)
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Jean-Louis Delaunay et al.
Hepatology (Baltimore, Md.), 65(2), 560-570 (2016-12-25)
ABCB4 (MDR3) is an adenosine triphosphate (ATP)-binding cassette (ABC) transporter expressed at the canalicular membrane of hepatocytes, where it mediates phosphatidylcholine (PC) secretion. Variations in the ABCB4 gene are responsible for several biliary diseases, including progressive familial intrahepatic cholestasis type
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The antiplatelet drug, ticlopidine (TIC), reportedly causes cholestatic liver injuries. The present study analyzed the effect of TIC on bile formation, revealing that the biliary secretion of phospholipids was significantly decreased in TIC-administered Sprague Dawley (SD) rats. However, the effect
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Electrophoresis, 37(17-18), 2376-2383 (2016-07-06)
Here, a compact high-speed CE bioanalyzer based on a short capillary has been developed. Multiple modules of picoliter scale sample injection, high-speed CE separation, sample changing, LIF detection, as well as a custom designed tablet computer for data processing, instrument
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