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Key Documents

M4125

Sigma-Aldrich

D-mannitolo

≥98% (GC)

Sinonimo/i:

Mannite

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About This Item

Formula empirica (notazione di Hill):
C6H14O6
Numero CAS:
Peso molecolare:
182.17
Beilstein:
1721898
Numero CE:
Numero MDL:
Codice UNSPSC:
12352201
ID PubChem:
NACRES:
NA.21

Origine biologica

plant

Livello qualitativo

Saggio

≥98% (GC)

Forma fisica

powder

Colore

white

Intervallo di pH utile

5.0-6.5 (25 °C, 182 g/L, (77 °F ))

Solubilità

water: 100 mg/mL, clear, colorless

Temperatura di conservazione

room temp

Stringa SMILE

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4-,5-,6-/m1/s1
FBPFZTCFMRRESA-KVTDHHQDSA-N

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Descrizione generale

D-Mannitol, a naturally occurring six-carbon sugar alcohol or polyol, is found in plants such as algae, onions, grasses, and olives. It is considered safe due to its relatively lower glycemic index than sucrose.

Applicazioni

D-Mannitol has been used:
  • in osmotic loading to adjust the osmolarity of solutions
  • as a component of test sugar solution for cellobiose-mannitol permeability test
  • as an internal standard in nuclear magnetic resonance (NMR) to compare/analyze the mannitol concentrations in urine samples
  • to treat the control cells and regulate the osmotic pressure of high glucose

D-mannitol has been used as a hydroxyl radical scavenger and as a medium supplement.

Azioni biochim/fisiol

D-Mannitol may play an important role in lipolysis and fat oxidation as it can enhance the phosphorylation of AMP-activated protein kinase (AMPK) and acetyl-CoA carboxylase 1 (ACC). It serves as an anti-obesity supplement. D-Mannitol stimulates the synthesis of short-chain fatty acids (SCFAs), which regulate lipid metabolism in the liver.
Un alcool dal sapore di zucchero dolce. Usato in test di inibizione del sapore dolce.

Altre note

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

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S J Upton et al.
Journal of clinical microbiology, 33(2), 371-375 (1995-02-01)
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To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. A prospective study. University hospital. Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. The participants completed a symptom questionnaire, recorded

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