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D8064

Sigma-Aldrich

4-(2-(6-(Dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)pyridinium hydroxide inner salt

≥95% purity (HPLC), solid

Sinonimo/i:

Di-4-ANEPPS

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About This Item

Formula empirica (notazione di Hill):
C28H36N2O3S
Numero CAS:
90134-00-2
Peso molecolare:
480.66
Numero MDL:
MFCD03453609
Codice UNSPSC:
12171500
ID PubChem:
329798855
NACRES:
NA.47

product name

4-(2-(6-(Dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)pyridinium hydroxide inner salt, ≥95% (HPLC), solid

Livello qualitativo

100

Saggio

≥95% (HPLC)

Forma fisica

solid

PM

480.66

Colore

orange to dark red

Solubilità

DMF: soluble
DMSO: soluble
ethanol: soluble

ε (coefficiente d’estinzione)

≥38000 at 493-499 nm in methanol

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

2-8°C

Stringa SMILE

CCCCN(CCCC)c1ccc2cc(\C=C\c3cc[n+](CCCS([O-])(=O)=O)cc3)ccc2c1

InChI

1S/C28H36N2O3S/c1-3-5-17-30(18-6-4-2)28-13-12-26-22-25(10-11-27(26)23-28)9-8-24-14-19-29(20-15-24)16-7-21-34(31,32)33/h8-15,19-20,22-23H,3-7,16-18,21H2,1-2H3
HAPJROQJVSPKCJ-UHFFFAOYSA-N

Categorie correlate

Applicazioni

4-(2-(6-(Dibutylamino)-2-naphthalenyl)ethenyl)-1-(3-sulfopropyl)pyridinium hydroxide inner salt has been used as a voltage sensitive dye in cardiac cells.

Azioni biochim/fisiol

Membrane potential dye that responds to changes in membrane potential monitored by fluorescence excitation changes at 440 and 505 nm; correlated to changes in membrane potential of the cell.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
MKCP7911
MKCP5626
MKCN3640
MKCH9277
MKCG5988

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Sigma-Aldrich

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Andrew D Bachtel et al.
IEEE transactions on bio-medical engineering, 58(7), 2120-2126 (2011-05-04)
We developed a new method for ratiometric optical mapping of transmembrane potential (V(m)) in cardiac preparations stained with di-4-ANEPPS. V(m)-dependent shifts of excitation and emission spectra establish two excitation bands (<481 and >481 nm) that produce fluorescence changes of opposite
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The voltage sensitivity of fluorescence of an aminobenzstyryl-pyridinium dye (di4-ANEPPS) is characterized in Retzius cells dissociated from the leech. The modulation of the complete spectra of excitation and emission is determined. The spectral changes induced by depolarization are described by
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