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D7008

Sigma-Aldrich

Dihydroethidium

≥95% purity, powder

Sinonimo/i:

2,7-Diamino-10-ethyl-9-phenyl-9,10-dihydrophenanthridine, 3,8-Diamino-5,6-dihydro-5-ethyl-6-phenylphenanthridine, Hydroethidine

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About This Item

Formula empirica (notazione di Hill):
C21H21N3
Numero CAS:
104821-25-2
Peso molecolare:
315.41
Beilstein:
5107482
Numero MDL:
MFCD00077335
Codice UNSPSC:
12171500
ID PubChem:
24894069
NACRES:
NA.47

product name

Dihydroethidium, ≥95%

Livello qualitativo

100

Saggio

≥95%

Forma fisica

powder

Colore

pink to very dark red

Solubilità

chloroform: 20 mg/mL

Fluorescenza

λex 370 nm; λem 420 nm (for cytoplasm of living cells)
λex 535 nm; λem 610 nm (for chromatin of living cells)

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

−20°C

Stringa SMILE

CCN1C(c2ccccc2)c3cc(N)ccc3-c4ccc(N)cc14

InChI

1S/C21H21N3/c1-2-24-20-13-16(23)9-11-18(20)17-10-8-15(22)12-19(17)21(24)14-6-4-3-5-7-14/h3-13,21H,2,22-23H2,1H3
XYJODUBPWNZLML-UHFFFAOYSA-N

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Categorie correlate

Applicazioni

Redox indicator. Blue fluorescence until oxidized to ethidium.
Dihydroethidium has been used as a superoxide probe in bovine pulmonary artery endothelial cell (BPAEC). It has been used to check the in situ generation of ROS (reactive oxygen species).

Confezionamento

Packaged under Argon.

Linkage

B-ring reduced analog of ethidium

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

06693

Timestrip Plus™ -20 °C

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
MKCN1192
MKCL7544
MKCL1719
MKCK8723
MKCK3321

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20-HETE increases superoxide production and activates NAPDH oxidase in pulmonary artery endothelial cells.
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Quercetin reduces oxidative stress and inhibits activation of c-Jun N-terminal kinase/activator protein-1 signaling in an experimental mouse model of abdominal aortic aneurysm.
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