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D3100000

Droperidol

European Pharmacopoeia (EP) Reference Standard

Sinonimo/i:

1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone

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About This Item

Formula empirica (notazione di Hill):
C22H22FN3O2
Numero CAS:
548-73-2
Peso molecolare:
379.43
Numero MDL:
MFCD00083290
Codice UNSPSC:
41116107
ID PubChem:
329798769
NACRES:
NA.24

Grado

pharmaceutical primary standard

Famiglia di API

droperidol

Produttore/marchio commerciale

EDQM

applicazioni

pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34

InChI

1S/C22H22FN3O2/c23-17-9-7-16(8-10-17)21(27)6-3-13-25-14-11-18(12-15-25)26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-5,7-11H,3,6,12-15H2,(H,24,28)
RMEDXOLNCUSCGS-UHFFFAOYSA-N

Informazioni sul gene

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

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Descrizione generale

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Applicazioni

Droperidol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Confezionamento

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Altre note

Sales restrictions may apply.

Prodotti correlati

N° Catalogo
Descrizione
Determinazione del prezzo

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H302

Classi di pericolo

Acute Tox. 4 Oral

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Lot/Batch Number

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Gregory A Nuttall et al.
Anesthesiology, 118(2), 382-386 (2013-01-08)
The Food and Drug Administration issued a black box warning regarding the use of droperidol and the potential for torsade de pointes. The primary objective of this retrospective study was to determine if low-dose (0.625 mg) droperidol administration was associated
Christopher Spevak et al.
Pain medicine (Malden, Mass.), 13(8), 1072-1080 (2012-06-12)
The most feared drug-induced complication is fatal cardiac arrest. Torsades de pointes (TdP) is a polymorphic ventricular tachycardia occurring in the setting of a QT interval prolongation and is the most frequent type of drug-induced pro-arrhythmia. The most common mechanism
Esther W Chan et al.
Annals of emergency medicine, 61(1), 72-81 (2012-09-18)
Parenteral benzodiazepines or antipsychotics are often used to manage acute agitation in emergency department (ED) settings in which alternative strategies have failed or are not feasible. There are scant data comparing parenteral medication regimens. We aim to determine the efficacy
Yi-Min Kuo et al.
Journal of the Chinese Medical Association : JCMA, 75(5), 227-233 (2012-05-29)
Droperidol is commonly added to intravenous patient-controlled analgesia (IVPCA) regimens as an antiemetic agent. Although some studies have demonstrated its safety and efficacy, it is not clear whether adding droperidol to IVPCA infusate without an extra loading dose can effectively
G Ormel et al.
Acta anaesthesiologica Scandinavica, 55(10), 1196-1205 (2011-11-19)
Prophylactic dexamethasone, ondansetron and droperidol have a documented effect on post-operative nausea and vomiting (PONV). Still, there is a lack of studies investigating the effect of adding dexamethasone to ondansetron and droperidol in order to treat established PONV. In this
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