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A8097

Sigma-Aldrich

Acridine Orange hydrochloride solution

>95.0% purity (HPLC), solution

Sinonimo/i:

3,6-Bis(dimethylamino)acridine hydrochloride

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About This Item

Formula empirica (notazione di Hill):
C17H19N3 · HCl
Numero CAS:
65-61-2
Peso molecolare:
301.81
Beilstein:
3575587
Numero MDL:
MFCD00012660
Codice UNSPSC:
12171500
ID PubChem:
24891317
NACRES:
NA.47

Nome del prodotto

Acridine Orange hydrochloride solution, 10 mg/mL in H2O, ≥95.0% (HPLC)

Livello qualitativo

200

Saggio

≥95.0% (HPLC)

Stato

solution

Concentrazione

10 mg/mL in H2O

tecniche

microbe id | staining: suitable

Colore

orange to red

εmax

47-54 at 486-492 nm in water

applicazioni

diagnostic assay manufacturing
hematology
histology

Temperatura di conservazione

room temp

Stringa SMILE

Cl[H].CN(C)c1ccc2cc3ccc(cc3nc2c1)N(C)C

InChI

1S/C17H19N3.ClH/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14;/h5-11H,1-4H3;1H
VSTHNGLPHBTRMB-UHFFFAOYSA-N

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Applicazioni

Acridine Orange hydrochloride solution has been used to study autophagic cell death. It has also been used for the staining of chromosomes.

Azioni biochim/fisiol

Acridine Orange is a metachromatic dye which can stain DNA, RNA and acid glycosaminoglycans. At low concentration it intercalates into DNA and precipitates RNA. However, at high concentration it denatures and precipitates both RNA and DNA. Acridine Orange is also used to analyze autophagy. It goes into acidic organelles in a pH-dependent manner. At neutral pH, acridine orange gives a green fluorescence and in acidic conditions, it accumulates in the acidic organelle giving a bright red fluorescence.

Pittogrammi

Health hazard
GHS08

Avvertenze

Warning

Indicazioni di pericolo

H341

Classi di pericolo

Muta. 2

Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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Certificati d'analisi (COA)

Lot/Batch Number
SLCK1031
SLCH5103
SLCG5311
SLCG5312
SLCF9286

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Sigma-Aldrich

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