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91275

Supelco

Propionyl-L-carnitine

analytical standard

Sinonimo/i:

(2R)-3-Carboxy-N,N,N-trimethyl-2-(1-oxopropoxy)-1-propanaminium inner salt, L-Carnitine propionyl ester, C3-Carnitine, Propanoyl-L-carnitine

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About This Item

Formula empirica (notazione di Hill):
C10H19NO4
Numero CAS:
Peso molecolare:
217.26
Numero MDL:
Codice UNSPSC:
41116107
NACRES:
NB.21

Grado

analytical standard

Livello qualitativo

Saggio

≥94.0% (HPLC)

Attività ottica

[α]/D -24.0±2.0°, c = 0.2 in H2O

Durata

limited shelf life, expiry date on the label

Impurezze

≤13% water ((calculated from elemental analysis)

applicazioni

clinical testing

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

[O-]C(C[C@@H](OC(CC)=O)C[N+](C)(C)C)=O

InChI

1S/C10H19NO4/c1-5-10(14)15-8(6-9(12)13)7-11(2,3)4/h8H,5-7H2,1-4H3/t8-/m1/s1
UFAHZIUFPNSHSL-MRVPVSSYSA-N

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Descrizione generale

Propionyl-L-carnitine (PLC), a natural odd-carbon-number, endogenous ester of L-carnitine, is found to be present in humans and animals as a minor component compared to L-carnitine (LC) and acetyl-L-carnitine (ALC). It acts as a carrier of long chain acyl groups from activated fatty acids across the inner mitochondrial membrane into the mitochondrial matrix where they undergo β-oxidation to acetyl CoA to obtain usable energy via the citric acid cycle.

Applicazioni

Propionyl-L-carnitine may be used as an analytical reference standard for the quantification of the analyte in biological samples using chromatography-based techniques. It may also be used as an analytical standard in monitoring the analyte in chemical synthesis procedures and pharmaceutical formulations using a stereospecific enzyme assay and high-performance liquid chromatography technique with UV detection.

Prodotti consigliati

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Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Certificati d'analisi (COA)

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I clienti hanno visto anche

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Application of high-performance liquid chromatography to the analysis of propionyl-L-carnitine by a stereospecific enzyme assay
Marzo A, et al.
Journal of Chromatography A, 459, 313-317 (1988)
Determination of L-carnitine, acetyl-L-carnitine and propionyl-L-carnitine in human plasma by high-performance liquid chromatography after pre-column derivatization with 1-aminoanthracene
Longo A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 686(2), 129-139 (1996)
Quantitation of L?carnitine, acetyl?L?carnitine, propionyl?L?carnitine and their deuterated analogues by high?performance liquid chromotography tandem mass spectrometry
Tallarico C , et al.
Rapid Communications in Mass Spectrometry, 12(7), 403-409 (1998)

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