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81210

Sigma-Aldrich

Poli(etilenglicole)

average Mw 1,500

Sinonimo/i:

PEG

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About This Item

Formula condensata:
H(OCH2CH2)nOH
Numero CAS:
25322-68-3
Numero MDL:
MFCD00081839
Codice UNSPSC:
12352104
ID PubChem:
24887690
NACRES:
NA.23

Forma fisica

solid

Livello qualitativo

200

PM

average Mw 1,500

Punto di fusione

45-50 °C

Temp. transizione

Tm 45-50 °C

Estremità Ω

hydroxyl

Estremità α

hydroxyl

Stringa SMILE

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Categorie correlate

Descrizione generale

Poly(ethylene glycol) (PEG) is a non-ionic hydrophilic polymer and is available in different molecular weights. It helps in the purification and crystal growth of proteins and nucleic acids. PEG and dextran together result in aqueous polymer two phase system, required for the purification of biological materials. PEG also interacts with cell membrane, thereby resulting in cell fusion.

Applicazioni

Poly(ethylene glycol) has been used for histological, histochemical and immunohistochemical evaluation of in vitro cultured beads. It has been used for the fusion of cells.

Altre note

Molecular weight range: 1,400-1,600

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)

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Certificati d'analisi (COA)

Lot/Batch Number
BCCD3122
BCCB0461
BCBX5256
BCBW2779
BCBT9003

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Poli(etilenglicole) average mol wt 400

Sigma-Aldrich

P3265

Poli(etilenglicole)

Poli(etilenglicole) average Mn 2,050, chips

Sigma-Aldrich

295906

Poli(etilenglicole)

Chondrogenesis of human mesenchymal stem cells encapsulated in alginate beads.
Ma HL et al.
Journal of Biomedical Materials Research Part A, 64, 273-273 (2003)
Poly (ethylene glycol) in drug delivery: pros and cons as well as potential alternatives.
Angewandte Chemie (International Edition in English), 49, 6288-6308 (2010)
DC-SIGN (CD209) expression is IL-4 dependent and is negatively regulated by IFN, TGF-beta, and anti-inflammatory agents.
Relloso M et al.
Journal of Immunology, 168, 2634-2634 (2002)
Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Applications (2013)
Idalis Villanueva et al.
Acta biomaterialia, 5(8), 2832-2846 (2009-06-11)
The pericellular matrix (PCM) surrounding chondrocytes is thought to play an important role in transmitting biochemical and biomechanical signals to the cells, which regulates many cellular functions including tissue homeostasis. To better understand chondrocytes interactions with their PCM, three-dimensional poly(ethylene
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Articoli

Degradable Poly(ethylene glycol) Hydrogels for 2D and 3D Cell Culture

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

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