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46166

Supelco

Dexamethasone 21-acetate

VETRANAL®, analytical standard

Sinonimo/i:

9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate

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About This Item

Formula empirica (notazione di Hill):
C24H31FO6
Numero CAS:
1177-87-3
Peso molecolare:
434.50
Beilstein:
2342608
Numero CE:
214-646-8
Numero MDL:
MFCD00027407
Codice UNSPSC:
41116107
ID PubChem:
329757093
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

100

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

clinical

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
AKUJBENLRBOFTD-RPRRAYFGSA-N

Informazioni sul gene

human ... NR3C1(2908)

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

Health hazard
GHS08

Avvertenze

Danger

Indicazioni di pericolo

H360FD

Classi di pericolo

Repr. 1B

Codice della classe di stoccaggio

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificati d'analisi (COA)

Lot/Batch Number
BCCK2179
BCBZ7482
SZBE045XV
SZB8004XV
SZBB084XV

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Xuefan Xu et al.
Drug delivery, 18(7), 485-492 (2011-06-23)
This work studied the intravenous injection formulation of nanostructured lipid carriers (NLCs) loaded with dexamethasone acetate (DA), a poorly water-soluble drug. The goal of this study was to design nanoparticles which could improve therapeutic efficacy of DA on inflammations. Based
Kam-Lun Ellis Hon et al.
The Journal of dermatological treatment, 19(4), 241-245 (2008-07-17)
Many parents purchase topical applications without knowing what they contain, and apply them liberally to their children with dermatological disorders. In one such case, an infant developed fever, diarrhea and a small ulcer near the right labia majora which was
T Lifshitz et al.
Ophthalmic surgery and lasers, 32(2), 159-161 (2001-04-13)
Retrocorneal membranes after penetrating keratoplasty (PKP) is a well known complications, resulting from unintentional retention of the host Descemet's membrane (DM), or donor DM detachment. We describe for the first time the formation of a retrocorneal inflammatory membrane that mimics
Sandra A L Moura et al.
Journal of pharmaceutical sciences, 100(7), 2886-2895 (2011-02-02)
Implants are defined as controlled sustained release delivery systems of therapeutic agents incorporated or dispersed into a polymeric carrier. These systems can be implanted in specific organs and delivered by the therapeutic agents at the target site to treat various
S L Fialho et al.
Current eye research, 31(6), 525-534 (2006-06-14)
The treatment of vitreoretinal diseases is limited and, nowadays, new drug delivery approaches have been reported in order to increase drug bioavailability. The objective of the current study was to determine the pharmacokinetic profile of a biodegradable dexamethasone acetate implant
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