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Documenti fondamentali

34218

Supelco

Cefuroxime

VETRANAL®, analytical standard

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About This Item

Formula empirica (notazione di Hill):
C16H16N4O8S
Numero CAS:
Peso molecolare:
424.39
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

clinical testing

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)\C(=N/OC)c3ccco3)C(O)=O

InChI

1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1
JFPVXVDWJQMJEE-IZRZKJBUSA-N

Descrizione generale

Cefuroxime is a new broad-spectrum cephalosporin antibiotic, with increased stability to β-lactamases. It is actively used against gram-positive organisms, including penicillinase-producing staphylococci and non-β-lactamase-producing gram-negative bacteria.
Chemical structure: ß-lactam

Applicazioni

Cefuroxime may be used as a reference standard in the determination of cefuroxime in plasma samples using high-performance liquid chromatography (HPLC).(3)
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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Certificati d'analisi (COA)

Lot/Batch Number

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Ronit Confino-Cohen et al.
The journal of allergy and clinical immunology. In practice, 5(3), 669-675 (2017-05-10)
Penicillins are the drug family most commonly associated with hypersensitivity reactions. Current guidelines recommend negative skin tests (ST) before re-administering penicillins to patients with previous nonimmediate reactions (NIR). The objective of this study was to examine whether ST are necessary
Till Junker et al.
Swiss medical weekly, 142, w13616-w13616 (2012-09-06)
Surgical site infections (SSI) are the most common hospital-acquired infections among surgical patients, with significant impact on patient morbidity and health care costs. The Basel SSI Cohort Study was performed to evaluate risk factors and validate current preventive measures for
Sathish Srinivasan et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 35(8), 538-542 (2019-08-09)
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Shiri Zarour et al.
American journal of surgery, 214(3), 456-461 (2017-02-27)
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Cefuroxime: human pharmacokinetics.
Foord DR.
Antimicrobial Agents and Chemotherapy, 9(5), 741-747 (1976)

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