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Documenti fondamentali

34039

Supelco

Marbofloxacin

VETRANAL®, analytical standard

Sinonimo/i:

9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-piperazino)-7-oxo-7H-pyrido[1,2,3-ij][1,2,4]benzoxadiazine-6-carboxylic acid, Zeniquin®

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About This Item

Formula empirica (notazione di Hill):
C17H19FN4O4
Numero CAS:
Peso molecolare:
362.36
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)

Formato

neat

Stringa SMILE

CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4N(C)COc2c34)C(O)=O

InChI

1S/C17H19FN4O4/c1-19-3-5-21(6-4-19)14-12(18)7-10-13-16(14)26-9-20(2)22(13)8-11(15(10)23)17(24)25/h7-8H,3-6,9H2,1-2H3,(H,24,25)
BPFYOAJNDMUVBL-UHFFFAOYSA-N

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Descrizione generale

Marbofloxacin belongs to the group of synthetic fluoroquinolone compounds, widely used as a veterinary anti-bacterial drug. It shows a broad spectrum of activity against both gram-positive and gram-negative bacteria.

Applicazioni

The analytical standard can be used as follows:
  • Surface-enhanced Raman spectroscopy-based determination of marbofloxacin in chicken and duck samples using β-cyclodextrin-modified silver nanoparticles (β-CD-AgNPs)
  • Analysis of synovial fluid and plasma samples obtained from dairy cows for marbofloxacin by high-performance liquid chromatography (HPLC) combined with tandem mass spectrometry (MS/MS) following ultrafiltration of the samples
  • Development of an indirect competitive ELISA (icELISA) method for the combined analysis of marbofloxacin and ofloxacin in raw milk and porcine samples
  • Multi-residue analysis of oxolinic acid, flumequine, marbofloxacin, and enrofloxacin in commercial honey samples by micellar liquid chromatography coupled with fluorescence detection
  • Simultaneous determination of marbofloxacin and trovafloxacin in sheep plasma samples by HPLC combined with UV detection
  • Quantification of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.

Altre note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany
Zeniquin is a registered trademark of Pfizer, Inc.

Indicazioni di pericolo

Consigli di prudenza

Classi di pericolo

Aquatic Chronic 3

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Dispositivi di protezione individuale

Gloves


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Certificati d'analisi (COA)

Lot/Batch Number

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Blood concentrations of marbofloxacin and its in vivo effect in yellow-bellied slider turtles (Trachemys scripta scripta) after a single intracoelomic injection at 3 dose rates.
Vercelli C, et al.
Journal of Exotic Pet Medicine, 25(4), 295-304 (2016)
Determination of marbofloxacin in plasma samples by high-performance liquid chromatography using fluorescence detection.
Garcia M A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 729(1-2), 157-161 (1999)
C Vilalta et al.
Journal of veterinary pharmacology and therapeutics, 37(6), 542-549 (2014-06-07)
This study evaluated the theoretical clinical outcome of three marbofloxacin posology regimens in two groups of pigs (weaners and fatteners) for the treatment of Actinobacillus pleuropneumoniae (App) and Haemophilus parasuis (Hp) infection and the appearance of resistant bacteria due to
Xiaoqiang Liu et al.
Veterinary microbiology, 174(3-4), 514-522 (2014-12-04)
This study explored and compared the mechanisms and selective concentration of resistance between a 3rd (pradofloxacin) and 2nd (ciprofloxacin) generation fluoroquinolone. Pradofloxacin- and ciprofloxacin-resistant mutants were selected by stepwise exposure of Escherichia coli (E. coli) to escalating concentrations of pradofloxacin
Seung Ryul Han et al.
Biochemical and biophysical research communications, 448(4), 397-402 (2014-05-06)
Danofloxacin is a synthetic fluoroquinolone with broad spectrum antibacterial activity that is used for the treatment of respiratory diseases in animal husbandry. However, danofloxacin has many adverse reactions and is toxic to humans. Especially, it detrimentally affects muscle, central nerve

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