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Key Documents

32671

Supelco

Carnidazole

VETRANAL®, analytical standard

Sinonimo/i:

[2-(2-Methyl-5-nitro-imidazol-1-yl)ethyl]thiocarbamic acid O-methyl ester

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About This Item

Formula empirica (notazione di Hill):
C8H12N4O3S
Numero CAS:
Peso molecolare:
244.27
Beilstein:
620260
Numero CE:
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

Durata

limited shelf life, expiry date on the label

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Formato

neat

Stringa SMILE

COC(=S)NCCn1c(C)ncc1[N+]([O-])=O

InChI

1S/C8H12N4O3S/c1-6-10-5-7(12(13)14)11(6)4-3-9-8(16)15-2/h5H,3-4H2,1-2H3,(H,9,16)
OVEVHVURWWTPFC-UHFFFAOYSA-N

Descrizione generale

Carnidazoles belong to the class of nitroimidazole compounds that are generally utilized for the treatment of various diseases in poultry, cattle and pigs.

Applicazioni

Carnidazole may be used as an analytical reference standard for the determination of the analyte in:
  • Eggs by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
  • Environmental water samples by dispersive liquid-liquid microextraction (DLLME), followed by micellar electrokinetic chromatography (MEKC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pittogrammi

CorrosionExclamation mark

Avvertenze

Danger

Indicazioni di pericolo

Classi di pericolo

Eye Dam. 1 - Skin Sens. 1

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves


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Certificati d'analisi (COA)

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Novel cation selective exhaustive injection-sweeping procedure for 5-nitroimidazole determination in waters by micellar electrokinetic chromatography using dispersive liquid-liquid microextraction.
Hernandez-Mesa, et al.
Journal of Chromatography A, 1341(46), 65-72 (2014)
P Chaudhuri et al.
European journal of obstetrics, gynecology, and reproductive biology, 10(5), 325-328 (1980-06-01)
A double-blind controlled clinical trial of the new, not yet commercially available drug, carnidazole and tinidazole, was carried out in 77 women with a proven vaginal trichomoniasis. 39 patients and their sexual partners received a single dose of 2 g
F F Franssen et al.
Journal of veterinary pharmacology and therapeutics, 15(4), 409-415 (1992-12-01)
Six out of eight different Trichomonas gallinae strains isolated from racing pigeons proved to be resistant to the nitroimidazole drugs ronidazole, carnidazole and metronidazole. The minimal cytocidal concentration of ronidazole was determined in in vitro experiments. Moreover, a therapeutic dose
Benjamin M Dudek et al.
Journal of wildlife diseases, 54(4), 755-764 (2018-06-05)
Avian trichomonosis, caused by the protozoan Trichomonas gallinae, affects bird-eating raptors worldwide. Raptors can develop trichomonosis by feeding on infected prey, particularly Rock Pigeons (C olumba livia), which are a reservoir for T. gallinae. Raptors may be particularly vulnerable to
Development and validation of a rapid method for the determination and confirmation of 10 nitroimidazoles in animal plasma using liquid chromatography tandem mass spectrometry.
Cronly M, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(14-15), 1494-1500 (2009)

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