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Merck
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Documenti fondamentali

32154

Supelco

Buparvaquone

VETRANAL®, analytical standard

Sinonimo/i:

2-[(4-tert-Butylcyclohexyl)methyl]-3-hydroxy-1,4-naphthoquinone, 2-[[4-(1,1-Dimethylethyl)cyclohexyl]methyl]-3-hydroxy-1,4-naphthalenedione

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About This Item

Formula empirica (notazione di Hill):
C21H26O3
Numero CAS:
Peso molecolare:
326.43
Numero MDL:
Codice UNSPSC:
41116107
ID PubChem:
NACRES:
NA.24

Grado

analytical standard

Livello qualitativo

Nome Commerciale

VETRANAL®

tecniche

HPLC: suitable
gas chromatography (GC): suitable

applicazioni

forensics and toxicology
veterinary

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

CC(C)(C)C1CCC(CC1)CC2=C(O)C(=O)c3ccccc3C2=O

InChI

1S/C21H26O3/c1-21(2,3)14-10-8-13(9-11-14)12-17-18(22)15-6-4-5-7-16(15)19(23)20(17)24/h4-7,13-14,24H,8-12H2,1-3H3
KLLIVCPQDTYMLC-UHFFFAOYSA-N

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Applicazioni

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Note legali

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Gantala Venkatesh et al.
Drug development and industrial pharmacy, 36(6), 735-745 (2010-02-09)
The aim of this study was to prepare a lipid-based self-microemulsifying drug delivery system (SMEDDS) to increase the solubility and oral bioavailability of a poorly water-soluble compound, buparvaquone (BPQ). The solubility of BPQ was determined in various vehicles, and pseudo-ternary
Juliana Q Reimão et al.
Experimental parasitology, 130(3), 195-199 (2012-01-28)
The objective of this study was to develop a novel liposomal formulation, containing phosphatidylserine (PS), of buparvaquone (BPQ) and to evaluate its in vivo effectiveness in Leishmania (L.) infantum chagasi-infected hamsters. The activity of BPQ was evaluated against both the
G R Muraguri et al.
Research in veterinary science, 81(1), 119-126 (2005-11-18)
East Coast fever, caused by the protozoan parasite Theileria parva, kills about 600,000 cattle annually in Africa. The hydroxynaphthoquinone compound buparvaquone (BPQ) is curative. Sixteen calves were infected with T. parva. On manifestation of disease symptoms, eight were injected with
Bariş Saruhan et al.
Turkiye parazitolojii dergisi, 32(4), 317-321 (2009-01-22)
The aim of this study was to examine the efficacy of buparvaquone (Buparvon, ALKE, Istanbul) in the treatment of theileriosis in cattle. The causative agent T. annulata causes direct and indirect gross economical loss in Turkey. Theileriosis was microscopically diagnosed
Tracy Garnier et al.
The Journal of pharmacy and pharmacology, 59(1), 41-49 (2007-01-18)
As the part of a study to develop buparvaquone (BPQ) formulations for the treatment of cutaneous leishmaniasis, the topical delivery of BPQ and one of its prodrugs from a range of formulations was evaluated. In previous studies, BPQ and its

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