SCT090

BioTracker Bacterial FtsZ Live Cell Dye

• Sinonimo/i: BioTracker Bacterial FtsZ Live Cell Dye
• Codice UNSPSC: 12352207

Proprietà

• Forma fisica: lyophilized
• PM: calculated mol wt 782.1
• Confezionamento: pkg of 1 mg
• Produttore/marchio commerciale: Millipore
• Condizioni di stoccaggio: protect from light
• Modalità di accrescimento: N/A
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

The filamentous temperature-sensitive Z (FtsZ) protein is a promising target for the development of new antibacterial drug targets. FtsZ is a protein encoded by the ftsZ gene that assembles into a ring at the future site of bacterial cell division and is one of the most conserved proteins in prokaryotes. This live cell probe will aid development of new FtsZ inhibitors and enable screening for FtsZ inhibition in a broad range of bacterial species. BioTracker Bacterial FtsZ Live Cell Dye is a BODIPY conjugated fluorescent probe that binds FtsZ proteins from both Gram-positive pathogens (Staphylococcus aureus, Enterococcus faecalis, Enterococcus faecium, Streptococcus pyogenes, Streptococcus agalactiae, and Streptococcus pneumoniae) and Gram-negative pathogens (Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii) (1). It allows for visualization of FtsZ using fluorescence microscopy, and can be used to monitor and identify non-fluorescent FtsZ inhibitors in these target pathogens. Spectral PropertiesExcitation: 488 nmEmission: 510 nmReference:1. Ferrer-González, Edgar, et al. "Structure-Guided Design of a fluorescent probe for the Visualization of ftsZ in clinically important Gram-positive and Gram-negative Bacterial pathogens." Scientific reports 9.1 (2019): 1-16.

Applicazioni

Purity ≥ 98% confirmed by HPLC. Identification confirmed by HNMR, LC-MS, and elemental analysis.

Caratteristiche e vantaggi

Fluorescence probe for detecting FtsZ in bacteria

Stato fisico

Lyophilized. Red solid.

Stoccaggio e stabilità

Store at -20°C, desiccate and protect from light.
Note: Centrifuge vial briefly to collect contents at bottom of vial before opening

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable