MABT186

Anti-Exo70 Antibody, clone 70X13F3

clone 70X13F3, from mouse

• Sinonimo/i: Exocyst complex component 7, Exocyst complex component Exo70, rExo70
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: 70X13F3, monoclonal
• Reattività contro le specie: human, rat
• tecniche: immunocytochemistry: suitable; western blot: suitable
• Isotipo: IgG2bκ
• N° accesso NCBI: NP_073182
• N° accesso UniProt: O54922
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... EXOC7(23265)

Descrizione

Descrizione generale

The exocyst complex component 70 (Exo70) is a component of the exocyst complex, an octameric structure that is also comprised of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70, and Exo84. The exocyst complex facilitates the fusion of secretory vesicles with the plasma membrane and the release of vesicular cargo, which may include neurotransmitters, hormones, and membrane proteins. Previous studies have indicated that Exo70 plays an important role in actin assembly and cell motility.

Immunogeno

GST-tagged recombinant protein corresponding to rat Exo70.

Applicazioni

Detect Exo70 using this Anti-Exo70 Antibody, clone 70X13F3 validated for use in Western Blotting, ICC.

Research Category
Cell Structure

Research Sub Category
Cytoskeletal Signaling

Western Blot Analysis: A 1:1,000 dilution from a representative lot detected Exo70 in 10 µg of human brain tissue lysate.
Immunocytochemistry Analysis: A representative lot was used by an independent laboratory in Exo70 cells. (Hsu, S.C., et al. (2001). The Journal of Neuroscience. 21(11):3839–3848.)
Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF. (Hsu, S.C., et al. (2011). The Journal of Neuroscience. 31(10):3522–3535.)

Qualità

Evaluated by Western Blot in rat brain tissue lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected Exo70 in 10 µg of rat brain tissue lysate.

Descrizione del bersaglio

~75 kDa observed

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Rat brain tissue lysate

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable