MABN666

Anti-TRIP8b Antibody, clone N212A/34

clone N212A/34, from mouse

• Sinonimo/i: PEX5-related protein, PEX5-like protein, Peroxin-5-related protein, TPR-containing Rab8b-interacting protein, Tetratricopeptide repeat-containing Rab8b-interacting protein, Pex5Rp, TRIP8b
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: N212A/34, monoclonal
• Reattività contro le specie: human, rat, mouse
• tecniche: western blot: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_775175
• N° accesso UniProt: Q925N3
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: rat ... Pex5L(286937)

Descrizione

Descrizione generale

Tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) is also called PEX5-related protein, PEX5-like protein and Peroxin-5-related protein (Pex5Rp). TRIP8b a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel subunit that is involved in HCN cynclic nucleotide dependence and expression at the cell surface. TRIP8b is expressed specifically in the brain.

Specificità

This antibody demonstrates specificity for TRIP8b containing exon 1b. It does not cross react with TRIP8b containing exons 1a, 2, or 4.

Immunogeno

Recombinant protein corresponding to rat TRIP8b.

Applicazioni

Anti-TRIP8b Antibody, clone N212A/34 is a highly specific mouse monoclonal antibody & that targets Tetratricopeptide repeat-containing Rab8b-interacting protein & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

Western Blotting Analysis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of human brain tissue lysate.

Western Blotting Analysis: A representative lot detected TRIP8b in COS cell lysates transiently transfected with GFP tagged TRIP8b (exon1b) and not in COS cell lysates transiently transfected with TRIP8b (exon1a, 2, or 4) or with untagged Kv2.1 plasmid (Prof. J. Trimmer, University of California, Davis.).

Qualità

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analyis: 0.5 μg/mL of this antibody detected TRIP8b in 10 μg of rat brain tissue lysate.

Descrizione del bersaglio

~70 kDa observed. Multiple isoforms may be observed due to alternative splicing (Lewis, A. S., et al. (2009). J Neurosci. 29(19):6250-6265.). Uncharacterized band(s) may be observed in some cell lysates.

Stato fisico

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Rat brain tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable