MABN501

Anti-SUR1 Antibody, clone N289/16

clone N289/16, from mouse

• Sinonimo/i: ATP-binding cassette sub-family C member 8, Sulfonylurea receptor 1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: mouse
• Livello qualitativo: 100
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: N289/16, monoclonal
• Reattività contro le specie: human, mouse
• Reattività contro le specie (prevista in base all’omologia): rat (immunogen homology)
• tecniche: immunohistochemistry: suitable; western blot: suitable
• Isotipo: IgG1κ
• N° accesso NCBI: NP_037171
• N° accesso UniProt: Q09429
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ABCC8(6833)

Descrizione

Descrizione generale

Sulfonylurea receptor 1 (SUR1) is also called ATP-binding cassette sub-family C member 8, and is a member of the ABC transporter superfamily. SUR1 is a putative subunit of the beta-cell ATP-sensitive potassium channel (KATP) and functions as a regulator of ATP-sensitive K+ channels and insulin release.

Specificità

This antibody recognizes the C-terminus of SUR1. Representative lot deteted Sur1 in crude brain membrane preparations
in SUR1 wild-type (WT) mouse cell lysate, and demonstrated a loss of signal in SUR1 knockout (KO) mouse cell lysate (Prof. J. Trimmer, University of California, Davis.).

Immunogeno

Recombinant protein corresponding to the C-terminus of rat SUR1.

Applicazioni

Anti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SUR1 in human thalamus tissue.

Qualità

Evaluated by Western Blotting in mouse hypothalamus tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected SUR1 in 10 µg of mouse hypothalamus tissue lysate.

Descrizione del bersaglio

~ 180 kDa observed

Stato fisico

Format: Purified

Risultati analitici

Control
Mouse hypothalamus tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable