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Key Documents

MAB8051

Sigma-Aldrich

Anti-Adenovirus Antibody, clone 2/6

clone 2/6, Chemicon®, from mouse

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

Forma dell’anticorpo

purified immunoglobulin

Clone

2/6, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

ELISA: suitable
flow cytometry: suitable
immunofluorescence: suitable
immunohistochemistry: suitable

Isotipo

IgG1κ

Condizioni di spedizione

wet ice

Descrizione generale

Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.

Specificità

All 41 serotypes of Adenovirus.

Applicazioni

Detect Adenovirus using this Anti-Adenovirus Antibody, clone 2/6 validated for use in ELISA, FC, IF, IH.
ELISA

IFA: acetone fixed cell preparations or tissues.

FACS: {McNees, 2004}

Dilute with buffer pH 7.5-8.0 to desired working volume.

For extensive dilution, protein containing or other stabilizing medium should be used.

Final working dilutions must be determined by end user.

Stato fisico

Format: Purified
Protein A-purified immunoglobulin. Liquid at 1 mg/mL in 20 mM phosphate buffer, containing 25 mM NaCl and 0.1% sodium azide, pH 7.6

Stoccaggio e stabilità

Maintain at 2-8°C in convenient aliquots for up to 12 months. Do not store in a diluted format.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 2

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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An outbreak of epidemic keratoconjunctivitis in a regional ophthalmology clinic in New South Wales.
K A Viney,P J Kehoe,B Doyle,V Sheppeard,A R Roberts-Witteveen,H Semirli,K A McPhie et al.
Epidemiology and Infection null
Modeling adenovirus latency in human lymphocyte cell lines.
Zhang, Y; Huang, W; Ornelles, DA; Gooding, LR
Journal of virology null
Protein crystals in Adenovirus type 5-infected cells: requirements for intranuclear crystallogenesis, structural and functional analysis.
Franqueville, L; Henning, P; Magnusson, M; Vigne, E; Schoehn, G; Blair-Zajdel, ME; Habib et al.
Testing null
Postinternalization inhibition of adenovirus gene expression and infectious virus production in human T-cell lines.
McNees, AL; Mahr, JA; Ornelles, D; Gooding, LR
Journal of virology null

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