GF101

CD40 Ligand/TRAP Protein, Recombinant human

The CD40 Ligand (CD40L/TRAP protein) is a type II membrane protein which, effectuates the helper function of T cells on resting B cells.

• Sinonimo/i: CD154, TRAP, TNF-related activation protein, T cell antigen Gp39
• Codice UNSPSC: 12352202
• eCl@ss: 32160405
• NACRES: NA.75

Proprietà

• Origine biologica: human
• Livello qualitativo: 100
• Saggio: >98% (SDS-PAGE and HPLC)
• Produttore/marchio commerciale: Chemicon^®
• tecniche: cell culture | mammalian: suitable
• Impurezze: <0.1 ng/μg Endotoxin (of sCD40L/TRAP; 1EU/μg)
• N° accesso NCBI: NM_000074.2
• N° accesso UniProt: P29965
• Condizioni di spedizione: dry ice
• Informazioni sul gene: human ... CD40LG(959)

Descrizione

Descrizione generale

CD40 Ligand (CD40L/TRAP) is a type II membrane protein which, effectuates the helper function of T cells on resting B cells. GF101 is a 16.3 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CD40L.

Product Source: Recombinant human

Stato fisico

Sterile filtered and lyophilized from 10 mM Sodium Phosphate, pH 7.5.

Stoccaggio e stabilità

The lyophilized protein is stable for a few weeks for at room temperature but is best stored at -20ºC. Reconstitute in water to 0.1-1.0 mg/ml. This solution can be diluted into other aqueous buffers and stored at 2-8ºC for one week or -20ºC for future use. Reconstituted sCD40L/TRAP should be stored at -20ºC in undiluted aliquots for up to 6 months. Freeze/thaw cycles will result in significant loss of activity.

Risultati analitici

Specific Activity: GF101 is fully biologically active as determined by its ability to stimulate the proliferation of HEK-BlueTMCD40 reporter cells.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1