FCABS301A4

Milli-Mark^® Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor^™488 Antibody

Milli-Mark^®, from rabbit

• Sinonimo/i: H3 histone family, member T, histone 3, H3, histone cluster 3, H3
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Coniugato: ALEXA FLUOR^™ 488
• Forma dell’anticorpo: purified immunoglobulin
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: human
• Produttore/marchio commerciale: Milli-Mark^®
• tecniche: flow cytometry: suitable
• Isotipo: IgG
• N° accesso NCBI: NP_003484
• N° accesso UniProt: Q16695
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: dimethylation (Lys9)
• Informazioni sul gene: human ... H3C1(8350)

Descrizione

Descrizione generale

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

Specificità

Antibody recognizes human Histone H3 dimethylated on lysine 9.

Immunogeno

Epitope: Methylated at Lys9dimethylated Lys 9 of Human Histone H3

KLH-conjugated, 2X-branched synthetic peptide corresponding to dimethyl-lysine at residue 9 of human Histone H3.

Applicazioni

Milli-Mark Anti-dimethyl-Histone H3 (Lys9)-Alexa Fluor488 Antibody detects level of dimethyl-Histone H3 (Lys9)-Alexa Fluor488 & has been published & validated for use in FC.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Histones

Qualità

Evaluated by flow cytometry using HeLa cells

Descrizione del bersaglio

15.5 kDa Calculated

Stato fisico

Protein A purified

Purified rabbit polyclonal IgG conjugated to Alexa Fluor 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA

Stoccaggio e stabilità

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Risultati analitici

Control
HeLa Cells

Note legali

ALEXA FLUOR is a trademark of Life Technologies

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable