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Key Documents

Altri documenti

CBL511

Sigma-Aldrich

Anti-CD55 Antibody, clone BRIC 216

clone BRIC 216, Chemicon®, from mouse

Sinonimo/i:

DAF

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About This Item

Codice UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Origine biologica

mouse

Livello qualitativo

100

Forma dell’anticorpo

affinity purified immunoglobulin

Tipo di anticorpo

primary antibodies

Clone

BRIC 216, monoclonal

Reattività contro le specie

human

Produttore/marchio commerciale

Chemicon®

tecniche

flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotipo

IgG1

N° accesso NCBI

NM_000574.2

N° accesso UniProt

P08174

Condizioni di spedizione

wet ice

Informazioni sul gene

human ... CD55(1604)

Specificità

This antibody recognizes the CD55 antigen a 70 kDa glycoprotein also known as Decay Accelerating Factor (DAF). The antigen is present on erthrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. It is found specifically at the placental fetal-maternal interface.

Immunogeno

Human fibroblast cell line

Applicazioni

Anti-CD55 Antibody, clone BRIC 216 is an antibody against CD55 for use in FC, IP, WB, IH, IH(P).
Research Category
Inflammation & Immunology
Research Sub Category
Immunoglobulins & Immunology
Western blot: Non-reduced erythrocyte membrane prep; antigen is sialidase and trypsin resistant, pronase, chymotrypsin and AET sensitive
Flow Cytometry
Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded sections. Protease antigen retreival is recommended.
Immunoprecipitation
Inhibition studies


Optimal working dilutions must be determined by the end user.

Stato fisico

Format: Purified
Protein G Purified
The immunoglobulin was purified from cell culture supernatant by affinity chromatography using protein G and is presented in 1 M Tris-buffered saline, pH 7.5, containing no preservatives. The antibody has been sterile-filtered.

Stoccaggio e stabilità

Aliquot antibody into small volumes and store at -20°C for up to 12 months from the date of receipt.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Preferential expression of the complement regulatory protein decay accelerating factor at the fetomaternal interface during human pregnancy.
Holmes, C H, et al.
Journal of immunology (Baltimore, Md. : 1950), 144, 3099-3105 (1990)
Mapping of epitopes, glycosylation sites, and complement regulatory domains in human decay accelerating factor.
Coyne, K E, et al.
Journal of immunology (Baltimore, Md. : 1950), 149, 2906-2913 (1992)
Kyle A Carver et al.
Investigative ophthalmology & visual science, 57(2), 360-371 (2016-02-05)
Oxidative stress is a major factor involved in retinal pigment epithelium (RPE) apoptosis that underlies AMD. Drusen, extracellular lipid- and protein-containing deposits, are strongly associated with the development of AMD. Cell-derived microparticles (MPs) are small membrane-bound vesicles shed from cells.

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