ABS72

Anti-WAS protein family homolog 1 (CT) Antibody

from rabbit

• Sinonimo/i: WAS protein family homolog 1, family with sequence similarity 39, member E, CXYorf1-like protein on chromosome 2, Protein FAM39E
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: mouse, human
• tecniche: western blot: suitable
• Isotipo: IgG
• N° accesso NCBI: NP_878908
• N° accesso UniProt: A8K0Z3
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... WASH1(100287171)

Descrizione

Descrizione generale

Wiskott-Aldrich Syndrome Protein and SCAR Homolog (WASH) is a novel protein belonging to the WASP family, a group of nucleation promoting factors (NFPs) that activate a critical component in endocytosis, Arp 2/3. WASH contains three specific domains: a C-terminal VCA domain, a proline-rich domain, and an N terminal region containing two WASH homolog regions, WHD1 and WHD2. Although WASH has yet to be completely characterized, it is known to function as an NPF at the endosomal surface, where it is involved in the recruitment and subsequent activation of Arp2/3 in order to initiate actin polymerization. Therefore, WASH has a crucial role in endosomal sorting as a mediator of tubule fission resulting from Arp2/3 activation.

Specificità

This antibody recognizes WAS protein family homolog 1 at the C-terminus.

Immunogeno

Epitope: C-terminus

GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus.

Applicazioni

Anti-WAS protein family homolog 1 (C-terminus) Antibody detects level of WAS protein family homolog 1 (C-terminus) & has been published & validated for use in WB.

Research Category
Signaling

Qualità

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected WAS protein family homolog 1 on 10 µg of HeLa cell lysate.

Descrizione del bersaglio

~ 60 kDa observed. The calculated molecular weight is 50 kDa

Stato fisico

Format: Purified

Protein G

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
HeLa cell lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable