ABN479

Anti-ATP2C1 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Calcium-transporting ATPase type 2C member 1, ATPase 2C1, ATP-dependent Ca(2+) pump PMR1, ATP2C1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse
• Reattività contro le specie (prevista in base all’omologia): human (immunogen homology)
• tecniche: immunohistochemistry: suitable; western blot: suitable
• N° accesso UniProt: P98194
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... ATP2C1(27032)

Descrizione

Descrizione generale

Calcium-transporting ATPase type 2C member 1 (ATP2C1) is a member of the cation transport ATPase (P-type) (TC 3.A.3) family. ATP2C1 catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen. It may also play an important role as a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. It is found in most tissues except colon, thymus, spleen and leukocytes.

Specificità

This antibody can recognize the three longest isoforms at ~101 kDa, ~103 kDa, and ~105 kDa.

Immunogeno

KLH-conjugated linear peptide corresponding to human ATP2C1.

Applicazioni

Anti-ATP2C1 Antibody is a highly specific rabbit polyclonal antibody, that targets Calcium-transporting ATPase type 2C member 1 & has been tested in western blotting & IHC.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected ATP2C1 in mouse brain tissue.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Qualità

Evaluated by Western Blotting/Peptide Inhibition Assay in mouse brain tissue lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected ATP2C1 in 15 µg of mouse brain tissue lysate.

Descrizione del bersaglio

~180 kDa observed. Uniprot describes 6 isoforms ranging between ~97 kDa and ~105 kDa Uncharacterized bands may appear in some lysate(s).

Stato fisico

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
Mouse brain tissue lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable