ABF218

Anti-STIM2 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Stromal interaction molecule 2, STIM2
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: human, mouse
• tecniche: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• N° accesso UniProt: Q9P246
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... STIM2(57620)

Descrizione

Descrizione generale

Stromal interaction molecule 2 (STIM2) plays an important role in mediating store-operated Ca2+ entry (SOCE), a Ca2+ influx following depletion of intracellular Ca2+ stores. It inhibits STIM1-mediated store-operated Ca++ entry; however, STIM2 can form complexes with STIM1. This suggests that STIM1 and STIM2 may play a coordinated role in controlling Ca++ entry. STIM2 is expressed in all tissues and tumor cell lines examined.

Specificità

This antibody recognizes the intermediate domain of STIM2.

Immunogeno

Epitope: Intermediate domain

KLH-conjugated linear peptide corresponding to the intermediate domain of human STIM2.

Applicazioni

Detect Stromal interaction molecule 2 using this rabbit polyclonal antibody, Anti-STIM2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected STIM2 in human spleen tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected STIM2 in human spleen cells.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Qualità

Evaluated by Western Blotting in A-20 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected STIM2 in 15 µg of A-20 cell lysate.

Descrizione del bersaglio

~98 kDa observed

Stato fisico

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
A-20 cell lysate

Altre note

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable