AB9882

Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody

Chemicon^®, from rabbit

• Sinonimo/i: HIP1R
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: purified antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Reattività contro le specie: mouse, rat, human
• Produttore/marchio commerciale: Chemicon^®
• tecniche: immunocytochemistry: suitable; western blot: suitable
• N° accesso NCBI: NM_003959.1
• N° accesso UniProt: O75146
• Condizioni di spedizione: dry ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... HIP1R(9026)

Descrizione

Descrizione generale

Huntingtin-Interacting protein-1 related (HIP1R) is an actin-binding protein that is considered an element of the clathrin-coated pits and vesicles and polymerizes actin. HIP1R is essential for normal actin organization and endocytosis. HIP1R is equipped with a epsin N-terminal homology domain which allows it to bind 3-phosphorylated inositol lipids, which allows HIP1R to function as a tyrosine kinase stabilizing receptor and plays a role in overall cell growth and survival.

Specificità

Huntingtin-interacting protein 1 related (HIP1R). By Western blot the antibody recognizes a band at ~116 kDa on P2 microsomal fraction from embryonic rat brain.

Immunogeno

Synthetic peptide

Applicazioni

Detect Huntingtin-Interacting Protein 1 Related (HIP1R) using this Anti-Huntingtin-Interacting Protein 1 Related (HIP1R) Antibody validated for use in WB & IC.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Synapse & Synaptic Biology

Western Blot: a 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.A 1:500-1:2,000 dilution of this antibody detected Huntingtin-interacting protein 1 related (HIP1R) in 10 µg of rat brain extract and mouse brain post-nuclear supernatant.

Immunocytochemistry: a previous lot of this antibody was used by an independent laboratory for IC of human cells. (Poupon, V., et al. (2008). PNAS. 105(1): 168-173.)

Optimal working dilutions must be determined by end user.

Descrizione del bersaglio

~116 kDa

Stato fisico

Format: Purified

Liquid

Stoccaggio e stabilità

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Note legali

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 10 - Combustible liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1