AB3503-I

Anti-PDX-1 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: mouse, human
• tecniche: immunohistochemistry: suitable; western blot: suitable
• N° accesso NCBI: NP_000200
• N° accesso UniProt: P52945
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... PDX1(3651)

Descrizione

Descrizione generale

Pancreatic and duodenal homeobox 1, also known as PDX1, and Insulin promoter factor 1 is a human gene. This islet-specific protein activates transcription of the insulin andsomatostatin genes. It is a key regulator of islet peptide hormone expressionn and also plays an essential role in pancreatic development. Mutations in this gene may be involved in several disorders of the pancreas or in diabetes mellitus.

Specificità

Recognizes PDX-1

Immunogeno

KLH-conjugated linear peptide corresponding to region amino acids 90-120 of human PDX-1.

Applicazioni

Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected pdx-1 in the islets of Langerhans of human and mouse pancreas.

This Anti-PDX-1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of PDX-1.

Qualità

Evaluated by Western Blotting in mouse pancreatic beta cell tissue lysate.

Western Blotting Analysis: A 1:4,000 dilution of this antibody detected PDX-1 in mouse pancreatic beta cell tissue lysate.

Descrizione del bersaglio

~38 kDa observed

Altre note

Concentration: Please refer to lot specific datasheet.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable