AB10541

Anti-Galectin-3 Antibody

from rabbit, purified by affinity chromatography

• Sinonimo/i: Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
• Codice UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Proprietà

• Origine biologica: rabbit
• Livello qualitativo: 100
• Forma dell’anticorpo: affinity isolated antibody
• Tipo di anticorpo: primary antibodies
• Clone: polyclonal
• Purificato mediante: affinity chromatography
• Reattività contro le specie: rhesus macaque, human
• Reattività contro le specie (prevista in base all’omologia): rhesus monkey (based on 100% sequence homology)
• tecniche: western blot: suitable
• N° accesso NCBI: NP_002297
• N° accesso UniProt: P17931
• Condizioni di spedizione: wet ice
• modifica post-traduzionali bersaglio: unmodified
• Informazioni sul gene: human ... LGALS3(3958)

Descrizione

Descrizione generale

Galectin-3 belongs to the galectin gene family, which is defined by the specificity of a carbohydrate recognition domain (CRD) for Gal/Lac. Galectin-3 expression is usually elevated in a wide range of neoplastic cell types. The galectin CRD consists of 135 amino acids. Galectin-3 is known to play a role in tumor development, apoptosis, and cell cycle progression.

Specificità

This antibody recognizes the Pro64 mutation domain of Galectin-3. It is equally specific for wild-type or mutant His64 Galectin-3.

Immunogeno

Epitope: Pro64 mutation domain

KLH-conjugated linear peptide corresponding to the Pro64 mutation domain of human Galectin-3.

Applicazioni

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Galectin-3 Antibody is validated for use in WB for the detection of Galectin-3.

Qualità

Evaluated by Western Blot in MG-63 cell lysate.

Western Blot Analysis: A 1:250 dilution of this antibody detected Galectin-3 in 10 µg of MG-63 cell lysate.

Descrizione del bersaglio

~33 kDa observed

Stato fisico

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stoccaggio e stabilità

Stable for 1 year at 2-8°C from date of receipt.

Risultati analitici

Control
MG-63 cell lysate

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 12 - Non Combustible Liquids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable