8.52124

Fmoc-Lys(Alloc)-OH

≥98.0% (HPLC), for peptide synthesis, Novabiochem^®

• Sinonimo/i: Fmoc-Lys(Alloc)-OH
• Formula empirica (notazione di Hill): C₂₅H₂₈N₂O₆
• Numero CAS: 146982-27-6
• Peso molecolare: 452.50
• Numero MDL: MFCD00190872
• Codice UNSPSC: 12352209
• NACRES: NA.22

Proprietà

• Nome del prodotto: Fmoc-Lys(Alloc)-OH, Novabiochem^®
• Livello qualitativo: 200
• Nome Commerciale: Novabiochem^®
• Saggio: ≥96.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• Stato: powder
• Impiego in reazioni chimiche: reaction type: Fmoc solid-phase peptide synthesis
• Produttore/marchio commerciale: Novabiochem^®
• Punto di fusione: 87-91 °C
• applicazioni: peptide synthesis
• Gruppo funzionale: amine
• Temperatura di conservazione: 2-30°C
• Stringa SMILE: N([C@@H](CCCCNC(=O)OCC=C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C25H28N2O6/c1-2-15-32-24(30)26-14-8-7-13-22(23(28)29)27-25(31)33-16-21-19-11-5-3-9-17(19)18-10-4-6-12-20(18)21/h2-6,9-12,21-22H,1,7-8,13-16H2,(H,26,30)(H,27,31)(H,28,29)/t22-/m0/s1; OJBNDXHENJDCBA-QFIPXVFZSA-N

Descrizione

Descrizione generale

Orthogonally-protected building block for the synthesis of branched and cyclic peptides and peptides modified at the Lys side chain by Fmoc SPPS. The Alloc group can be selectively removed in the presence of standard Fmoc- and t-butyl-based protecting groups by treatment with Pd(Ph₃P)₄/CHCl₃/AcOH/NMM.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Guide to Selection of Orthogonally -Protected Building Blocks for Fmoc SPPS

Linkage

Replaces: 04-12-1305

Risultati analitici

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Optical rotation α 25/D (c=1 in DMF): -13.5 - -11.0 °
Purity (TLC(157A)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 96.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Note legali

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 3
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable