8.52111

Fmoc-Lys(Me)₂-OH HCl

≥95.0% (HPLC), for peptide synthesis, Novabiochem^®

• Sinonimo/i: Fmoc-Lys(Me)₂-OH HCl, N-α-Fmoc-N-ε-dimethyl-N-L-lysine · hydrochloride
• Formula empirica (notazione di Hill): C₂₃H₂₈N₂O₄ · xHCl
• Numero CAS: 252049-10-8
• Peso molecolare: 396.48 (free base basis)
• Numero MDL: MFCD05662353
• Codice UNSPSC: 12352209
• NACRES: NA.22

Proprietà

• Nome del prodotto: Fmoc-Lys(Me)₂-OH HCl, Novabiochem^®
• Livello qualitativo: 200
• Nome Commerciale: Novabiochem^®
• Saggio: ≥95% (TLC); ≥95.0% (HPLC)
• Stato: powder
• Impiego in reazioni chimiche: reaction type: Fmoc solid-phase peptide synthesis
• Produttore/marchio commerciale: Novabiochem^®
• applicazioni: peptide synthesis
• Gruppo funzionale: amine
• Temperatura di conservazione: -10 to -25°C
• Stringa SMILE: Cl.N([C@@H](CCCCN(C)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C23H28N2O4.ClH/c1-25(2)14-8-7-13-21(22(26)27)24-23(28)29-15-20-18-11-5-3-9-16(18)17-10-4-6-12-19(17)20;/h3-6,9-12,20-21H,7-8,13-15H2,1-2H3,(H,24,28)(H,26,27);1H/t21-;/m0./s1; SJFAFKDBWNFBCC-BOXHHOBZSA-N

Descrizione

Descrizione generale

A novel derivative for the introduction of dimethyl-lysine during Fmoc SPPS. Ref ^[1] contains methods and protocols for the synthesis of arrays of histone-related peptides containing methylated arginine and lysine-residues.


Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Overcoming Aggregation in Fmoc SPPS

Literature references

^[1] S. Rothbart, et al. (2012) Methods Enzymol., 512, 107.

Linkage

Replaces: 04-12-1269

Risultati analitici

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA1)): ≥ 95 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Acetate (IC): ≤ 1.0 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Note legali

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 2
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable