648480

Troponin I, Human Heart

• Sinonimo/i: Troponin I, Human Heart, hcTnI
• Numero CAS: 77108-40-8
• Numero MDL: MFCD00213059
• Codice UNSPSC: 12352202
• NACRES: NA.32

Proprietà

• Saggio: ≥95% (SDS-PAGE)
• Livello qualitativo: 100
• Forma fisica: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze
• Solubilità: urea/Tris buffer (0.02 M Tris, HCl, pH 7.5, 7 M urea, 5 mM EDTA, 15 mM 2-mercaptoethanol): 1 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of Tnl in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for anti-sera production. Also useful as a tracer for iodination.

Native troponin I purified from human heart. Inhibitory subunit of troponin that binds to actin in the absence of Ca²⁺, thus inhibiting the ATPase activity of actomyosin. Presence of hcTnI in plasma has been used for early detection of myocardial infarction. Useful as a standard in immunoassay and as an immunogen for antisera production. Also useful as a tracer for iodination.

Attenzione

Toxicity: Standard Handling (A)

Stato fisico

Lyophilized from 10 mM HCl.

Nota sulla preparazione

Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Altre note

Falahati, A., et al. 1999. Am. Heart J. 137, 332.
Mangano, D.T. 1994. Anesthesiology 81, 1317.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany